Results 181 to 190 of about 10,535,256 (359)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Patient-Specific Lumped-Parameter Model for Quantifying Vessel-Specific Remodeling and Predicting Right Ventricular Function in Pulmonary Hypertension. [PDF]

Compr Physiol
Lechuga CG, Kachabi A, Colebank MJ, Korcarz CE, Raza F, Chesler NC.   +5 more
europepmc   +1 more source

Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry

, 2017
Priyanka Nandakumar, Dongwon Lee, Melissa A. Richard, Fasil Tekola‐Ayele, Bamidele O. Tayo, Erin B. Ware, Yun Ju Sung, Babatunde Salako, Adesola Ogunniyi, C. Charles Gu, Megan L. Grove, Myriam Fornage, Sharon L.R. Kardia, Charles N. Rotimi, Stephen S. Rich, Alanna C. Morrison, Georg Ehret, Aravinda Chakravarti   +17 more
openalex   +2 more sources

Dietary Sodium Consumption Predicts Future Blood Pressure and Incident Hypertension in the Japanese Normotensive General Population [PDF]

, 2015
Hiroyuki Takase, Tomonori Sugiura, Genjiro Kimura, Nobuyuki Ohte, Yasuaki Dohi   +4 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Topological Photonic Crystal Ring Resonator Pressure Sensor in the Optical Communication Range. [PDF]

Sensors (Basel)
Wu M, Yang Z, Fei H, Lin H.
europepmc   +1 more source

Associations between active travel and weight, blood pressure and diabetes in six middle income countries: a cross-sectional study in older adults [PDF]

, 2015
Anthony A Laverty, Raffaele Palladino, John Tayu Lee, Christopher Millett   +3 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Improved Pressure Sensing Performance of Self-Powered Electrochemical Pressure Sensor Using a Simple Electrode Coplanar Structure. [PDF]

Sensors (Basel)
Han Y, Duan Z, Wang Y, Chen W, Liu D, Yuan Z, Jiang Y, Tai H.   +7 more
europepmc   +1 more source

Small-size temperature/high-pressure integrated sensor via flip-chip method [PDF]

Mimi Huang, Xiaoyu Wu, Libo Zhao, Xiangguang Han, Yong Xia, Yi Qin Gao, Zeyu Cui, Cheng Zhang, Xiaokai Yang, Zhixia Qiao, Zhikang Li, Feng Han, Ping Yang, Zhuangde Jiang   +13 more
openalex   +1 more source