Results 51 to 60 of about 5,609,198 (311)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

High pressure Raman study and phase transitions of KIO3 non-linear optical single crystals

, 1998
Potassium iodate KIO3 single crystal samples have been studied under pressure up to 35 GPa at room temperature. Drastic spectral changes and phase transitions were observed. The first phase transition occurs at 5.
Zhou, F., Li, H. P., Tang, S. H, Wang, X. B., Shen, Z. X   +4 more
core   +1 more source

Pressure-Responsive Polymer Chemosensors for Hydrostatic-Pressure-Signal Detection: Poly‑l‑Lysine–Pyrene Conjugates

, 2023
Stimulus-responsive polymer materials are an attractive alternative to conventional supramolecular and polymer assemblies for applications in sensing, imaging, and drug-delivery systems.
Gaku Fukuhara (1472686), Yoshitane Imai (1864159), Soshi Wakako, Keiichi Nakagawa, Gaku Fukuhara, Tadashi Mori (1271277), Yumiko Hori (14671433), Koki Hasegawa (3738022), Keiichi Nakagawa (818625), Yoshitane Imai, Takao Saiki (17080518), Tomokazu Kinoshita, Xinyi Qi, Soshi Wakako (17080515), Tomokazu Kinoshita (9211620), Koki Hasegawa, Xinyi Qi (11833058), Yumiko Hori, Tadashi Mori, Takao Saiki   +19 more
core   +1 more source

NbN-based Josephson junctions grown by plasma-assisted molecular beam epitaxy

Communications Materials
Improved process for the growth of NbN by plasma-assisted molecular beam epitaxy (PAMBE) is needed for the fabrication of Josephson junctions, that are building blocks of qubits in quantum computers.
Artur Lachowski, Paweł Wolny, Krzysztof Dybko, Mikołaj Chlipała, Krzesimir Nowakowski-Szkudlarek, Mateusz Hajdel, Mikołaj Żak, Anna Feduniewicz, Marta Sawicka, Witold Chromiński, Ewa Grzanka, Czesław Skierbiszewski   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Pressure ulcer related pain in community populations: a prevalence survey. [PDF]

, 2014
BACKGROUND: Pressure ulcers are costly to the healthcare provider and can have a major impact on patient's quality of life. One of the most distressing symptoms reported is pain.
McGinnis, Elizabeth, Coleman, S, McGinnis, E, Wilson, L, Briggs, Michelle, Michelle Collinson, Nelson, EA, Susanne Coleman, Briggs, M; id_orcid, Collinson, Michelle, Stevenson, Rebecca, Dealey, C, Stubbs, N, E Andrea Nelson, Jane Nixon, Dealey, Carol, Michelle Briggs, Briggs, M, Nixon, J, Stevenson, R, Lyn Wilson, Nikki Stubbs, Brown, Julia, Nelson, E Andrea; id_orcid, Collinson, M, Coleman, Susanne, Elizabeth McGinnis, Nixon, Jane, Rebecca Stevenson, Wilson, Lyn, Julia Brown, Stubbs, Nikki, Carol Dealey, Brown, J   +33 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Blood pressure monitoring in sleep: time to wake up [PDF]

, 2020
Hypertension is a highly common condition with well-established adverse consequences. Ambulatory blood pressure monitoring has repeatedly been shown to better predict cardiovascular outcomes and mortality, compared to single office visit blood pressure ...
박성하
core   +1 more source