Results 121 to 130 of about 4,038,581 (311)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Design and Validation of 3D-Printed Personalized Seat Inserts for Truck Drivers
Applied SciencesProfessional truck drivers spend prolonged periods seated, often leading to discomfort and fatigue. Conventional seats are typically designed for average body dimensions rather than individual morphology, which limits their ability to provide optimal ...
Boris Steenhuis +3 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
ComputationTwin-screw compressors (TSCs) are widely used in various industries. Their performance is influenced by several parameters, such as rotor profiles, clearance gaps, operating speed, and thermal effects. Traditionally, optimizing these parameters relied on
Ildiko Brinas +4 more
doaj +1 more source
Non-uniform Braneworld Stars: an Exact Solution
, 2008 The first exact interior solution to Einstein's field equations for a static and non-uniform braneworld star with local and non-local bulk terms is presented.
Brown R. A. +8 more
core +2 more sources
FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Meitan kexue jishuIn order to reveal the pressure distribution and fluid migration law of the gas lift reverse circulation washing flow field in drilling method, the ø5m advanced drilling of the north wind well in Taohutu coal mine was taken as the research background ...
Longhui GUO +5 more
doaj +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
TekstilecConventional brassiere underwires often cause discomfort due to localized pressure concentrations, leading to wearer discomfort and potential long-term health concerns.
Dhivya Sugumaran, Samuel Wesley
doaj +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source