Results 51 to 60 of about 2,768,115 (243)

Simulation d’une filtration liquide en canal poreux fermé à une extrémité avec prise en compte de la formation du dépôt [PDF]

, 2009
La formation d’un dépôt de filtration ainsi que les performances de filtration associées ont été étudiées par CFD en utilisant un maillage mobile.
CABASSUD, Corinne, SCHMITZ, Philippe, GUIGUI, Christelle, MENDRET, Julie   +3 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Implementation of Cellulose-Based Filtration Aids in Industrial Sunflower Oil Dewaxing (Winterization): Process Monitoring, Prediction, and Optimization

Foods
In the production of refined sunflower oil, waxes are removed during the winterization stage, and wax crystals are separated through filtration assisted by filtration aids.
Tanja Lužaić, Katarina Nedić Grujin, Lato Pezo, Branislava Nikolovski, Zoran Maksimović, Ranko Romanić   +5 more
doaj   +1 more source

Effect of pore pressure distribution on fracture behavior of sandstone in nitrogen fracturing

Energy Exploration & Exploitation, 2017
To investigate the effect of pore pressure distribution on fracture behavior of rock in gas fracturing, nitrogen fracturing experiments on the sandstone are performed under different gas filtration conditions. Results indicate that the breakdown pressure
Peng Hou, Feng Gao, Yanan Gao, Yugui Yang, Chengzheng Cai   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Experimental study on filtration behavior and control methods of pre-pad CO2 fracturing fluids in shale oil reservoirs

Shiyou shiyan dizhi
To investigate the filtration behavior and control mechanisms of novel carbon dioxide (CO2) fracturingfluid systems suitable for shale reservoirs, systematic comparative experiments were conducted under simulated formation conditions using natural shale ...
Hui CHEN, Xiaopeng CAO, Hongxin ZHANG, Jianhui DUAN, Fei FAN, Junping BEI, Dehui CHEN   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation of microbiological variants of sputum processing and concentration of mycobacteria to optimize the microscopic and imaging diagnosis of tuberculosis

International Journal of Mycobacteriology, 2019
Background: Direct sputum smear is still the first-choice tool for screening of tuberculosis worldwide. Variants of this technique, to improve the sensitivity are desired.
Jorge E Coronel, Christian C Del Carpio, Erwin J Dianderas, Edgar A Florentini, Guillermo L Kemper, Patricia Sheen, Mirko J Zimic   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source