Results 181 to 190 of about 91,606 (298)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Spreading of ground pressure fluctuation in the gob

open access: yes, 2016
Досліджено процес поширення флуктуації гірського тиску у виробленому просторі діючого очисного вибою. Встановлено залежність величини затримки прояву флуктуації у вигляді збурення напружено-деформованого стану масиву від її амплітуди та розподілу ...
Назимко, В.В.   +1 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Tide-induced air pressure fluctuation in coastal unsaturated zones

open access: yes, 2003
Air pressure in coastal unsaturated aquifers fluctuates with sea tides, as does the groundwater level. Tide-induced air pressure fluctuations in coastal subsurface systems, however, are not well addressed in literature.
Li, H, Jiao, JJ
core  

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