Results 91 to 100 of about 2,248,909 (304)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Preeclampsia in women with pregestational diabetes – a cohort study
Aims: To evaluate risk factors for preeclampsia (PE) in women with pregestational diabetes. Methods: Retrospective cohort study of women with pregestational diabetes cared for at a specialized prenatal care facility.
Maria Lúcia Da Rocha Oppermann +4 more
doaj +1 more source
Cortisol Secreting Adrenal Adenoma in a 5 Year Old Child [PDF]
Adrenal adenoma is a rare endocrinal tumor in children. It can present with features of Cushing's syndrome. We present a case report of five years old female child who came with morbid obesity and hypertension.
Narang, Gursharan Singh +1 more
core
Thermodynamic Limits of Work and Pressure Gain in Combustion and Evaporation Processes [PDF]
Combustion and evaporation processes occurring in a closed chamber can result in significant pressure rise and direct work transfer. The pressure and volumetric changes that accompany such processes allow substantial work potential to be achieved in ...
Nalim, M. Razi
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Generation of adverse pressure gradient in the circumferential flashback of a premixed flame [PDF]
Circumferential upstream propagation of a premixed flame in a region confined between two concentric tubes is considered. The cold flow in this configuration features rotational motion and the flame is modelled as an interface separating the burned and ...
Brown, Phillip +4 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Treatment of high blood pressure and gain in event-free life expectancy
Behrouz Kassaï, Jean-Pierre Boissel, Michel Cucherat, Florent Boutitie, François GueyffierDepartment of Clinical Pharmacology, Claude Bernard University, Lyon, FranceObjective: Consideration of absolute risk has been recommended for making ...
Behrouz Kassaï +4 more
doaj
Relaminarization of pipe flow by means of 3d-printed shaped honeycombs
Based on a novel control scheme, where a steady modification of the streamwise velocity profile leads to complete relaminarization of initially fully turbulent pipe flow, we investigate the applicability and usefulness of custom-shaped honeycombs for ...
Hof, Björn +2 more
core +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source

