Results 41 to 50 of about 410,014 (263)

Parametric sensitivity of a CFD model concerning the hydrodynamics of trickle-bed reactor (TBR)

Chemical and Process Engineering, 2016
The aim of the present study was to investigate the sensitivity of a multiphase Eulerian CFD model with respect to relations defining drag forces between phases. The mean relative error as well as standard deviation of experimental and computed values of
Janecki Daniel, Burghardt Andrzej, Bartelmus Grażyna   +2 more
doaj   +1 more source

Influence of Non-Newtonian Viscosity on Flow Structures and Wall Deformation in Compliant Serpentine Microchannels: A Numerical Study

Micromachines, 2023
The viscosity of fluid plays a major role in the flow dynamics of microchannels. Viscous drag and shear forces are the primary tractions for microfluidic fluid flow.
Khemraj Deshmukh, Kunal Mitra, Arindam Bit   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A family of adverse pressure gradient turbulent boundary layers with upstream favourable pressure gradients

Journal of Fluid Mechanics, 2023
A flat-plate turbulent boundary layer (TBL) is experimentally subjected to a family of 22 favourable–adverse pressure gradients (FAPGs) using a ceiling panel of variable convex curvature. We define FAPGs as a sequence of streamwise pressure gradients in the order of favourable followed by adverse, similar in sequence to the pressure gradients over the ...
Aadhy Parthasarathy, Theresa Saxton-Fox
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Modeling Flow and Pressure Fields in Porous Media with High Conductivity Flow Channels and Smart Placement of Branch Cuts for Variant and Invariant Complex Potentials

Fluids, 2019
A long overdue distinction between so-called variant and invariant complex potentials is proposed here for the first time. Invariant complex potentials describe physical flows where a switch of the real and imaginary parts of the function will still ...
Aadi Khanal, Ruud Weijermars
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Surrogate Model with a Deep Neural Network to Evaluate Gas–Liquid Flow in a Horizontal Pipe

Energies, 2020
This study developed a data-driven surrogate model based on a deep neural network (DNN) to evaluate gas−liquid multiphase flow occurring in horizontal pipes.
Yongho Seong, Changhyup Park, Jinho Choi, Ilsik Jang   +3 more
doaj   +1 more source