Results 101 to 110 of about 4,376,058 (346)

Revised Friction Groups for Evaluating Hydraulic Parameters: Pressure Drop, Flow, and Diameter Estimation

open access: yesJournal of Marine Science and Engineering
Suitable friction groups are provided for solving three typical hydraulic problems. While the friction group based on viscous forces is used for calculating the pressure drop or head loss in pipes and open channels, commonly referred to as the Type 1 ...
Dejan Brkić
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Gait analysis in clinically healthy sheep from three different age groups using a pressure-sensitive walkway

open access: yesBMC Veterinary Research, 2012
Background Understanding normal gait requires allowing for variations in normal patterns by the sex, age, and species in question. Therefore, the aim of this study was to evaluate kinetic and temporospatial parameters in clinically healthy sheep from ...
Agostinho Felipe S   +6 more
doaj   +1 more source

Pressure Groups and Experts in Environmental Regulation [PDF]

open access: yes
We study a problem of adverse selection in the context of environmental regulation, where the firm may suffer from a certain degree of ignorance about its own type. In a framework like the construction of a certain infrastructure project, the presence of
Porteiro, Nicol?
core  

P Wave Dispersion is Increased in Pulmonary Stenosis [PDF]

open access: yes, 2006
Aim: The right atrium pressure load is increased in pulmonary stenosis (PS) that is a congenital anomaly and this changes the electrophysiological characteristics of the atria.
Cebeci, Bekir Sitki   +5 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Permeation of Global Governance by Pressure Groups [PDF]

open access: yes, 2017
n domestic politics, pressure groups are viewed warily. The founders of the United States, for instance, warned about the “mischiefs of faction” and strived to create a political system that would moderate their influence.
Johnson, Tana
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Serendipitous Catch of a Giant Jellyfish: An Ionized Nebula around 3C 275.1 with 170 kpc Long Tails

open access: yesThe Astrophysical Journal
3C 275.1 is a blue quasar at z = 0.55522, hosting powerful outflows and residing in a complex environment. We present a serendipitously detected giant nebula surrounding 3C 275.1, which shows morphological features resembling those of objects known as ...
Qinyuan Zhao, Junfeng Wang, Zhenzhen Li
doaj   +1 more source

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