Results 91 to 100 of about 3,560,028 (306)
Age-related hearing loss and blood pressure
Noise and Health, 2006 A review of the literature studying possible correlations between hearing function and cardiovascular disease (CVD) reveals a complex and somewhat contradictory picture. Most studies favor the concept of an association between hearing loss and CVD. The issue of interactions between noise-induced hearing loss and CVD, as well as between age-related ...
Ulf, Rosenhall, Valter, Sundh
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Construction and application of flow pressure drop model of perforated well considering pressure loss of perforation hole. [PDF]
Sci Rep, 2023 Jiang H, Wu M, Zheng Y, Zhao Q, Gao Y.
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Well design as a factor contributing to loss of water from the Floridan Aquifer, eastern Clay County, Florida [PDF]
, 1962 A number of wells penetrating the Floridan aquifer in eastern Clay County were found to be losing water to permeable zones above this aquifer. A differential in artesian pressure was observed in closely spaced wells of similar depth.
Foster, James B.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Simulation and Optimization of Throttle Flowmeter with Inner-Outer Tube Element
Measurement Science Review, 2017 In order to solve the dilemma between the smaller pressure loss and the larger flow measurement signal in traditional throttle flowmeters, a throttle structure with the inner-outer tube was designed and analyzed.
Meng Jiang +3 more
doaj +1 more source
Efficacy of endotracheal tube clamping to prevent positive airways pressure loss and pressure behavior after reconnection: a bench study. [PDF]
Intensive Care Med Exp, 2023 Bulleri E +8 more
europepmc +1 more source
Inverse versus Normal NiAs Structure as High-Pressure Phase of FeO and MnO
, 1997 The high-pressure phases of FeO and MnO were studied by the first principles calculations. The present theoretical study predicts that the high-pressure phase of MnO is a metallic normal B8 structure (nB8), while that of FeO should take the inverse B8 ...
Fang, Z. +4 more
core +1 more source