Results 71 to 80 of about 5,597,666 (293)

Joint statistics between velocity-gradient and fluctuating pressure in a turbulent planar jet

open access: yesNihon Kikai Gakkai ronbunshu, 2017
Joint statistics between velocity gradient and fluctuating static pressure in a turbulent planar jet are experimentally investigated. The experimental data was acquired by simultaneous measurements of velocity gradient ( ∂u’2/∂x1 and ∂u’1/∂x2, where u’1,
Mamoru TAKAHASHI   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Homogeneous Vessels as Active Elements for Measuring Pressure [PDF]

open access: yes, 2018
This work investigates an approach to pressure sensor design in which a homogeneous vessel is used as the active element to sense pressure. The goal of this project was to synthesize a standard model for the design and development of a pressure sensor ...
Nash, Michael
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Intra-Tissue Pressure Measurement in Ex Vivo Liver Undergoing Laser Ablation with Fiber-Optic Fabry-Perot Probe

open access: yesSensors, 2016
We report the first-ever intra-tissue pressure measurement performed during 1064 nm laser ablation (LA) of an ex vivo porcine liver. Pressure detection has been performed with a biocompatible, all-glass, temperature-insensitive Extrinsic Fabry-Perot ...
Daniele Tosi   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Blood Pressure Measurement. [PDF]

open access: yesPostgraduate Medical Journal, 2000
Blood Pressure Measurement. Produced by the British Hypertension Society. BMJ Publishing Group; £47.00. ISBN 0727-913743. \**\*|\* This CD-ROM specifies on its outside cover, in some detail, the minimum system requirements. These will not be met by all equipment currently in use in medical libraries nor by bottom of the range home computing.
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Comparison of straight line curve fit approaches for determining parameter variances and covariances

open access: yesInternational Journal of Metrology and Quality Engineering, 2020
Pressure balances are known to have a linear straight line equation of the form y = ax + b that relates the applied pressure x to the effective area y, and recent work has investigated the use of Ordinary Least Squares (OLS), Weighted Least Squares (WLS),
Ramnath Vishal
doaj   +1 more source

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