Results 111 to 120 of about 646,805 (301)

Performance of the LHCb Vertex Detector Alignment Algorithm determined with Beam Test Data

, 2008
LHCb is the dedicated heavy flavour experiment at the Large Hadron Collider at CERN. The partially assembled silicon vertex locator (VELO) of the LHCb experiment has been tested in a beam test. The data from this beam test have been used to determine the
Akiba, K., Artuso, M., Borel, J., Bowcock, T.J.V., Buytaert, J., Collins, P., de Vries, H., Dumps, R., Dwyer, L., Eckstein, D., Eklund, L., Ferro-Luzzi, M., Frei, R., Gersabeck, M., Haefeli, G., Hennessy, K., Huse, T., Jans, E., John, M., Ketel, T.J., Keune, A., Lastovicka, T., Mountain, R., Neufeld, N., Papadelis, A., Parkes, C., Stone, S., Szumlak, T., Tobin, M., Van Beuzekom, M., Van Lysebetten, A., Versloot, T.W., Viret, S., Wang, J.C.   +33 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

First principles modeling of pure black phosphorus devices under pressure

Beilstein Journal of Nanotechnology, 2019
Black phosphorus (BP) has a pressure-dependent bandgap width and shows the potential for applications as a low-dimensional pressure sensor. We built two kinds of pure BP devices with zigzag or armchair conformation, and explored their pressure-dependent ...
Ximing Rong, Zhizhou Yu, Zewen Wu, Junjun Li, Bin Wang, Yin Wang   +5 more
doaj   +1 more source

Systems and methods for measuring component matching [PDF]

, 2006
Systems and methods for measuring a contour match between adjacent components are disclosed. In one embodiment, at least two pressure sensors are located between adjacent components.
Courter, Kelly J., Slenk, Joel E.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Measurement of Spatio-Temporal Gait Parameters Through a Wearable Device for the Evaluation of the Activity Level of Athletes

IEEE Open Journal of Instrumentation and Measurement
Wearable technologies support athletes and coaches by providing objective data to enhance performance, prevent injuries, and optimize training. magnetic and inertial measurement units (MIMUs) measure spatio-temporal parameters, enabling the analysis of ...
Luna Panni, Gloria Cosoli, Marco Arnesano, Federico Citarelli, Luca Antognoli, Lorenzo Scalise   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Quantum sensing of local magnetic field texture in strongly correlated electron systems under extreme conditions

, 2018
An important feature of strong correlated electron systems is the tunability between interesting ground states such as unconventional superconductivity and exotic magnetism. Pressure is a clean, continuous and systematic tuning parameter. However, due to
Chen, Yang, Goh, Swee K., Ho, Kin On, Kasahara, S., Matsuda, Y., Mizukami, Y., Shibauchi, T., Yang, Sen, Yip, King Yau, Yu, King Yiu, Zhang, Wei   +10 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source