Results 101 to 110 of about 176,311 (260)

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Ayurveda management of chronic non healing pressure ulcer at foot secondary to tethered cord syndrome – A case report

Indian Journal of Ayurveda and Integrative Medicine KLEU, 2018
Pressure ulcers are classic chronic ulcers that appear over the areas of pressure and trauma in the skin that has lost sensation. Tethered cord syndrome is a rare etiology of chronic pressure ulcer originating from the central nervous system.
Ramesh Killedar, Rajashekhar Sanapeti, Pradeep Shindhe   +2 more
doaj  

Construction of risk prediction model for pressure ulcer of elderly patients underwent hip joint replacement in ICU

Huli yanjiu, 2022
ObjectiveTo analyze influence factors of pressure ulcer of elderly patients underwent hip joint replacement in intensive care unit（ICU），and to construct a risk prediction model.Methods248 elderly patients underwent hip joint replacement in ICU of a ...
DONG Zhenghui, LI Yang, QI Jinfang, LI Zhengang, WANG Zhiwei, TAO Zhenzhen   +5 more
doaj  

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Ayurveda management of chronic non healing pressure ulcer at foot, secondary to tethered cord syndrome –A case report

Indian Journal of Ayurveda and Integrative Medicine KLEU, 2019
Pressure ulcers are classic chronic ulcers that appear over the areas of pressure and trauma in the skin that has lost sensation. Tethered cord syndrome is a rare etiology of chronic pressure ulcer originating from the central nervous system.
Ramesh Killedar, Rajashekhar Sanapeti, Pradeep Shindhe   +2 more
doaj  

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

Do pressure ulcer risk assessment scales improve clinical practice?

Journal of Multidisciplinary Healthcare, 2010
Jan Kottner1, Katrin Balzer21Department of Nursing Science, Charité-Universitätsmedizin Berlin, Germany; 2Nursing Research Group, Institute for Social Medicine, Universitätsklinikum Schleswig-Holstein, Lübeck ...
Jan Kottner, Katrin Balzer
doaj  

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

The Random Forest Model Has the Best Accuracy Among the Four Pressure Ulcer Prediction Models Using Machine Learning Algorithms

Risk Management and Healthcare Policy, 2021
Jie Song,1 Yuan Gao,2 Pengbin Yin,3 Yi Li,1 Yang Li,2 Jie Zhang,4 Qingqing Su,1 Xiaojie Fu,2 Hongying Pi5 1Medical School of Chinese PLA, Beijing, People’s Republic of China; 2First Medical Center, Chinese PLA General Hospital, Beijing, People ...
Song J, Gao Y, Yin P, Li Y, Li Y, Zhang J, Su Q, Fu X, Pi H   +8 more
doaj