Results 101 to 110 of about 2,497,341 (230)

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

A NEW APPROACH TO PEDIATRIC BURNS: COMPARING STABLE OZONIDES AND SILVER SULPHADIAZINE

A NEW APPROACH TO PEDIATRIC BURNS: COMPARING STABLE OZONIDES AND SILVER SULPHADIAZINE Serena Crucianelli1 , Guido Ciprandi2 , Francesca Grussu2 , Francesco Spione2 , Paolo Dicorato2 , Mara Pisani3 1 Sapienza University of Rome, Internal Medicine ...
SERENA CRUCIANELLI, Paolo Dicorato, Guido Ciprandi, Francesca Grussu, Francesco Spione, Mara Pisani   +5 more
core  

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Establishment and application of pressure ulcer assessment scale for surgical patients

Huli yanjiu, 2018
Objective:To develop a pressure ulcer risk assessment scale for surgical patients,and provide a scientific and effective assessment tool for accurately assessing the pressure ulcer risk of surgical patients.Methods:Through literature inquiry,group ...
张誉璇, 敬洁
doaj  

Prediction Pressure Ulcers in High Care Unit Patients: Evaluating Risk Factors and Predictive Scale Using a Prospective Cross-Sectional Study

Avicenna Journal of Medicine
Background The incidence of ulcer pressure in the high care unit (HCU) was relatively high and could be reliably predicted using tools such as the Norton and Jackson/Cubbin scales.
Anies Dewi Wirati Indraswari, Umi Aisyiyah, Kurniawan Kurniawan, Meircurius Dwi Condro Surboyo   +3 more
doaj   +1 more source

Pressure Ulcer of the Pinna [PDF]

Ear, Nose & Throat Journal, 2013
Mainak, Dutta, Soumya, Ghatak, Ramanuj, Sinha   +2 more
openaire   +2 more sources

NEW PROTOCOL FOR IAD TREATMENT IN PEDIATRIC PATIENTS: STABLE OZONIDES

NEW PROTOCOL FOR IAD TREATMENT IN PEDIATRIC PATIENTS: STABLE OZONIDES Serena Crucianelli1 , Guido Ciprandi2 , Mauro Pace3 , Valentina Vanzi4 , Monica Rossi5 , Giancarlo Antonielli6 1 Sapienza University of Rome, Internal Medicine and Medical ...
SERENA CRUCIANELLI, Mauro Pace, Valentina Vanzi, Guido Ciprandi, Monica Rossi, Giancarlo Antonielli   +5 more
core