Results 141 to 150 of about 114,956 (306)

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

British Journal of Clinical Pharmacology, EarlyView.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez, Gülnihal Özcan, Hakan S. Orer   +2 more
wiley   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

An interprofessional approach to pressure ulcer prevention: a knowledge and attitudes evaluation

, 2019
Paul Clarkson,1,2 Peter R Worsley,1 Lisette Schoonhoven,1,3 Dan L Bader11School of Health Sciences, University of Southampton, Southampton, UK; 2Southern Health NHS Foundation Trust, Calmore, UK; 3Julius Center for Health Sciences and Primary Care ...
Schoonhoven L, Bader DL, Worsley PR, Clarkson P   +3 more
core  

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF‐07261271 in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim There is an unmet need for more effective therapies in inflammatory bowel disease (IBD). A single drug that blocks multiple distinct pathogenic pathways may offer therapeutic benefit superior to current monotherapies. PF‐07261271, a bispecific antibody targeting both the p40 subunit of interleukin‐12/23 and tumour necrosis factor‐like cytokine 1A ...
Srividya Neelakantan, Christopher Banfield, Kenneth Hung, Anna Sapone, Vivek Pradhan, Yuxi Zhao, Dana Parsons‐Rich, Grace Lee, Bryce G. Johnson, Elena Peeva, Michael S. Vincent, Valerie M. Clerin   +11 more
wiley   +1 more source

Incidence, Bacterial Growth Pattern and Antibiotic Sensitivity of Patient With Pressure Ulcer in Dr.Soetomo General Hospital Surabaya [PDF]

: Pressure ulcer is a condition often found in chronically ill patients with prolonged immobilization. Infected pressure sore can inhibit wound healing, wound treatment and worsen the patient's condition.
Iswinarno Doso Saputro, Iswinarno, Kevin Andana H.S, Kevin, Damayanti, Damayanti   +2 more
core  

Lowering salivary pH with sugar‐containing gum augments salivary nitrite production and blood pressure reduction with dietary nitrate (beetroot juice)

British Journal of Clinical Pharmacology, EarlyView.
Acutely lowering salivary pH (with sugar‐containing acidic gum vs. sugar‐free gum) augments salivary nitrate reduction to nitrite, plasma nitrite concentration, and blood pressure lowering with dietary nitrate. Modifying salivary pH reveals a mechanism by which the nitrate‐nitrite‐NO pathway may be upregulated/inhibited, with potential for other ...
Andrew J. Webb, Harriet Clift, Callum Hill, Nur Mousa, Navanithan Arun Jayaraj, Jasmine Quraishi, Charlotte E. Mills, Kevin O'Gallagher   +7 more
wiley   +1 more source

A systematic review of neuromuscular electrical stimulation for pressure ulcer care in spinal cord injuries.

, 2014
Introduction and Aim Pressure ulcer (PU) is one of the most common secondary complications following a spinal cord injury (SCI). Electrical stimulation (ES) can confer the benefit to pressure ulcer care in SCI.
Gall, Angela, Moody, Julie, Dyson, Sue E., Liu, Liang Q., Traynor, Michael   +4 more
core  

Pressure Ulcer of the Pinna [PDF]

Ear, Nose & Throat Journal, 2013
Mainak, Dutta, Soumya, Ghatak, Ramanuj, Sinha   +2 more
openaire   +2 more sources

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Nurses' knowledge, attitudes, and practices in pressure ulcer prevention in intensive care units: associations with burnout. [PDF]

PeerJ
Shahin MAH, Elgazzar SE, Hussien RM, Elsehrawy MG.   +3 more
europepmc   +1 more source