Results 91 to 100 of about 187,934 (352)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Differential associations of the stages of pressure and stasis ulcers and social engagement among nursing home residents

Aging and Health Research
Background: Social engagement is an important determinant of health in older adults. Skin ulcers may adversely impact social engagement among nursing home residents.
Anyah Prasad, Anthony P. Nunes, Bill M. Jesdale, Natalia N. Nielsen, Catherine E. Dubé, Deborah S. Mack, Kate L. Lapane   +6 more
doaj   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Pressure ulcer incidence in Dutch and German nursing homes: design of a prospective multicenter cohort study

BMC Nursing, 2011
Background Pressure ulcers are a common and serious health care problem in all health care settings. Results from annual national pressure ulcer prevalence surveys in the Netherlands and Germany reveal large differences in prevalence rates between both ...
Lohrmann Christa, Heinze Cornelia, Halfens Ruud JG, Meesterberends Esther, Schols Jos MGA   +4 more
doaj   +1 more source

Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review

Advanced Science, EarlyView.
This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren, Fuyao Liu, Yanan Zhong, Shengbo Ge, Zhipeng Shi, Siling Lin, Hongli Song, Yingying Zhang, Wei Fan   +8 more
wiley   +1 more source

Larval therapy for leg ulcers (VenUS II) : randomised controlled trial [PDF]

, 2009
Objective To compare the clinical effectiveness of larval therapy with a standard debridement technique (hydrogel) for sloughy or necrotic leg ulcers. Design Pragmatic, three armed randomised controlled trial.
Bland, J. Martin, Cullum, Nicky, Dowson, Christopher G., Dumville, Jo C., HASH(0x55aa08b64cf0), Iglesias, Cynthia, Mitchell, Joanne L., Nelson, E. Andrea, Soares, Marta O., Torgerson, David J., Worthy, Gill   +10 more
core   +3 more sources

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Reading Man Flap for Sacral Pressure Ulcer Reconstruction

, 2021
Tawfeeq Waleed Tawfeeq, Afraa Qasim Al-Zerkani, Sinan Adil Abdulateef   +2 more
openalex   +2 more sources

Retracted: Design for Bedridden Elderly: Presenting Pressure Ulcer Product Design Based on Anthropometric Characteristics [PDF]

, 2023
Computational Intelligence and Neuroscience
openalex   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source