Results 161 to 170 of about 14,747 (270)

Greening academia: developing sustainable waste management at UK higher educational institutions

, 2011
Dealing with municipal solid waste has become a problematic issue in the United Kingdom (UK). With actions to mitigate the potentially adverse impacts of climate change debate and space for, and costs of, landfill becoming critical, a landfilldominated ...
Zhang, Na
core  

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

A Coast-to-Coast Assessment of Cumulative Impacts and Protection Potential in Canadian Marine Conservation Networks. [PDF]

Environ Manage
Murphy GEP, Agbayani S, Nelson JC, Rubidge EM, Stanley RRE, Murray CC, Kelly NE.   +6 more
europepmc   +1 more source

Ecosystem services and marine conservation

, 2015
International audienceMarine and land ecosystems provide many benefits to society. Marine ecosystems are under increased pressure because of climate change, expanding human populations and needs.
Bailly, Denis, Quillérou, Emmanuelle, Mongruel, Rémi   +2 more
core  

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Tree cover loss in the Americas: a critical indicator linking climate mitigation and planetary health. [PDF]

Lancet Reg Health Am
Rojas-Rueda D, Valdés-Ortega N, Hartinger SM.   +2 more
europepmc   +1 more source

Understanding the interactions among local communities, protected areas and tourism: case studies of Kruger National Park and Purnululu National Park

, 2010
New management approaches for protected areas emphasise a 'humans in nature' perspective, with protected areas seen as intrinsically connected with surrounding human populations. Tourism often provides a connection between these communities and protected
Strickland-Munro, Jennifer. K.
core  

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

Advanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh, Ki‐bum Lee, Junghyeon Lee, Seunghee Cho, Malkeshkumar Patel, Hangfei Li, Yu Wen, Ye Zhou, Joondong Kim   +8 more
wiley   +1 more source

Habitat and Anthropogenic Determinants of Otter Presence in the Karnali River, Western Nepal. [PDF]

Ecol Evol
Acharya M, Subba A, Pandey N, Khanal L.
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source