Results 1 to 10 of about 3,229 (163)
Development of a Next-Generation Sequencing Protocol for Assessing Lenacapavir Resistance in HIV-1 Capsid. [PDF]
ABSTRACT Lenacapavir (LEN) is a first‐in‐class capsid inhibitor (CAI) that targets multiple stages of the HIV‐1 lifecycle, showing efficacy in heavily treatment‐experienced (HTE) individuals with multidrug‐resistance (MDR) and in pre‐exposure prophylaxis (PrEP). This study aimed to characterize a novel in‐house next‐generation sequencing (NGS) protocol
El Khalili O +10 more
europepmc +2 more sources
Harnessing metabolic control for synaptic stability: REST/NRSF links glycolytic inhibition to excitatory neurotransmission. [PDF]
Abstract figure legend Schematic of REST/NRSF‐dependent postsynaptic downscaling of excitatory strength in response to glycolysis inhibition Glycolysis inhibition enhances REST/NRSF expression and increases REST/NRSF transcriptional repressor activity by promoting its translocation into the nucleus.
Ferrante D +10 more
europepmc +2 more sources
Este artículo resultado de una investigación doctoral se apoyó en la teoría del consumo estatutario para describir el impacto social de la apropiación de los dispositivos móviles en las prácticas de prestigio y diferenciación de grupos pertenecientes a ...
Diana Esperanza Oliveros Fortiche
doaj +5 more sources
We observe a relevant growth in teacher’s perception of reduction of their social prestige, even if it seems stable according to the occupational prestige scales.
Gianluca Argentin
doaj +5 more sources
Immunological and virological response to fostemsavir in routine US clinical care: An OPERA cohort study. [PDF]
Abstract Objectives Fostemsavir is a novel attachment inhibitor used with other antiretrovirals in heavily treatment‐experienced (HTE) adults with multidrug‐resistant HIV‐1. Real‐world immunological and virological responses were assessed in individuals starting fostemsavir in the OPERA cohort.
Hsu RK +9 more
europepmc +2 more sources
Aumenta así la presión por publicar pero en formatos definidos, estandarizados, esto, en tanto se debe publicar en revistas indexadas y sobre todo, indexadas en bases bibliográficas de impacto, este es un sistema que no escapa a la lógica capitalista ...
Eulalia Borja Bedoya +1 more
doaj +4 more sources
Escala argentina de prestigio ocupacional
El esquema de desarrollo del trabajo es el siguiente: a) en un primer punto, se presenta una discusion teorica sucinta sobre diversas alternativas de construccion de escalas de prestigio ocupacional; b) en un segundo punto, se describe el enfoque adoptado en esta investigacion; c) en un tercer punto, se discuten problemas de validez y confiabilidad de ...
Jorge Raúl Jorrat
exaly +2 more sources
Percepciones lingüísticas de los jóvenes universitarios mallorquines hacia el andaluz
Las actitudes lingüísticas de los distintos grupos de hablantes explican muchas de sus actuaciones comunicativas y de sus ideales lingüísticos. Esta investigación, enmarcada en el proyecto PRECAVES XXI, se ha centrado en determinar a través de un ...
Beatriz Méndez Guerrero
doaj +1 more source
Cohort profile: PRESTIGIO, an Italian prospective registry-based cohort of people with HIV-1 resistant to reverse transcriptase, protease and integrase inhibitors [PDF]
Tommaso Clemente +2 more
exaly +2 more sources
Abstract Introduction Although debate remains about the saliency and relevance of pro‐choice and pro‐life labels (as abortion belief indicators), they have been consistently used for decades to broadly designate abortion identity. However, clear labels are less apparent in other languages (e.g., Spanish).
Danny Valdez +4 more
wiley +1 more source

