Results 141 to 150 of about 452,364 (380)
Beyond the Constitution? Englishness in a post-devolved Britain [PDF]
, 2008 The notion that we are currently witnessing a growing commitment to English nationalism and deeper and wider identification with Englishness, as opposed to Britishness, is becoming part of the political wisdom of the age.
English, Richard +2 more
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Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
The Social Construction of Sexuality in Primary School Classrooms [PDF]
, 2014 Through qualitative interviews with primary school teachers, this research sought to uncover how heterosexual privilege is maintained in talk about sexuality.
Spengen, Anna
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The myth of the overworked American [PDF]
A challenge to the popular presumption that U.S. workers are experiencing declining levels of leisure time, finding that the total hours of work have not changed much over the past decade, but that the composition of labor has shifted from home work to ...
Kristin Roberts, Peter Rupert
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The Diversity Distraction: A Critical Comparative Analysis of Discourse in Higher Education Scholarship [PDF]
, 2019 This critical literature review investigates how diversity and equity are employed in top-cited higher education scholarship published between 2000 and 2015.
Byrd, Derria
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Is the Price Elasticity of Money Demand Always Unity? [PDF]
Including both monetary gold and nonmonetary gold in a standard money-in-utility model, we establish a presumption that the price elasticity of money demand should be less than one under commodity standards.
Paul Evans, Xiaojun Wang
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