Results 211 to 220 of about 40,113 (297)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Experiences and Correlates of Cyber Dating Abuse in Sexual and Gender Minority Adolescent Girls and Feminine Teens: Implications for Psychological Wellbeing. [PDF]
Wongsomboon V +3 more
europepmc +1 more source
Чому конституційну формулу принципу презумпції невинуватості треба змінити.(The constitutional formula of the presumption of innocence must be changed.) [PDF]
В. О. Попелюшко
openalex
Preventive Justice and the Presumption of Innocence
Kimberly Kessler Ferzan
openalex +2 more sources
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Mining the Gaps: Rethinking Divergence Between Biological and Self-Report Measures in the Study of Sexual Diversity. [PDF]
Diamond LM.
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Renal hydatid cyst mimicking malignancy: a case report. [PDF]
Maghbool M, Dehghani MR, Samizadeh B.
europepmc +1 more source

