Results 321 to 330 of about 439,022 (382)

Safety evaluation of the food enzyme asparaginase from the non-genetically modified <i>Saccharomyces cerevisiae</i> strain ARY-2. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Fernàndez-Fraguas C, Cavanna D, Peluso S, Liu Y.   +16 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

A Malignant Masquerade: Angiosarcoma Presenting as an Impending Rupture of an Abdominal Aortic Aneurysm. [PDF]

Cureus
Tamaoka K, Shimamoto T, Sakamoto K, Takehara M.   +3 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of <i>Bacillus velezensis</i>NRRL B-67647, <i>Bacillus pumilus</i>NRRL B-67648 and <i>Bacillus licheniformis</i>NRRL B-67649 (Microsaf®) for chickens for fattening, other poultry for fattening and ornamental birds (S.I. Lesaffre). [PDF]

EFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Villa RE, Azimonti G, Bonos E, Christensen H, Durjava M, Dusemund B, Gehring R, Glandorf B, Kouba M, López-Alonso M, Marcon F, Nebbia C, Pechová A, Prieto-Maradona M, Röhe I, Theodoridou K, Mayo B, Anguita M, Cionci NB, Brozzi R, Innocenti ML, Ortuño J, Valeri P, García-Cazorla Y.   +24 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Comprehensive genome-wide analysis for the safety assessment of microbial biostimulants in agricultural applications. [PDF]

Microb Genom
Bellotti G, Cortimiglia C, Antinori ME, Cocconcelli PS, Puglisi E.   +4 more
europepmc   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Don't kill Granny, send her to the gym! [PDF]

Br J Gen Pract
Bethell H.
europepmc   +1 more source