Results 151 to 160 of about 53,341 (352)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

SCIENTIFIC LEGAL TERMINOLOGY IN FORMAL AND INFORMAL INTERPRETATIONS OF LAW

open access: yesВестник Кемеровского государственного университета, 2015
The paper deals with the regularities of scientific interpretation of legal terms. To realize this purpose, we compared the scientific definitions of the two legal terms: “presumption of innocence” and “authentic interpretation of the law”.
E. V. Gorodishenina
doaj  

Staging colorectal cancer with the TNM 7(th): the presumption of innocence when applying the M category. [PDF]

open access: yesWorld J Gastroenterol, 2013
Puppa G   +5 more
europepmc   +1 more source

ПРЕЗУМПЦІЯ НЕВИНУВАТОСТІ ЗА ЗАКОНОМ, НА ГРАНІ ЗАКОНУ ТА ПОЗА ЙОГО МЕЖАМИ (Presumption of Innocence According to the Law, Bordering on Law, and Beyond the Law) [PDF]

open access: yes, 2008
Розглядаються питання законодавчого визначення та наукового розуміння принципу презумпції невинуватості, прояву відступів від його вимог, обґрунтовується висновок про необхідність кардинальних змін відносно нього.
Попелюшко, В. (V.Popeliushko)
core  

Preventive Justice and the Presumption of Innocence

open access: yesCriminal Law and Philosophy, 2013
When the state aims to prevent responsible and dangerous actors from harming its citizens, it must choose between criminal law and other preventive techniques. The state, however, appears to be caught in a Catch-22: using the criminal law raises concerns about whether early inchoate conduct is properly the target of punishment, whereas using the civil ...
openaire   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

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