Results 161 to 170 of about 58,278 (391)
On the issue of the principle of the presumption of innocence in disciplinary proceedings
S. V. Davydenko, V. A. Slivnaya
openalex +2 more sources
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Preventive Justice and the Presumption of Innocence
Kimberly Kessler Ferzan
openalex +2 more sources
Perierapan Yurisdiksi Alien Tort Claim Act dalam Perspektif Hukum Pidana Internasional [PDF]
ATCk restricts its jurisdiction by imposing some doctrines such as minimum contact, forum non-convenience, political question, International commuty and act of state doc trine.
sefriani, S. (sefriani)
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
SCIENTIFIC LEGAL TERMINOLOGY IN FORMAL AND INFORMAL INTERPRETATIONS OF LAW
The paper deals with the regularities of scientific interpretation of legal terms. To realize this purpose, we compared the scientific definitions of the two legal terms: “presumption of innocence” and “authentic interpretation of the law”.
E. V. Gorodishenina
doaj
Death in the time of Covid-19: Efforts to restore the death penalty in the Philippines. [PDF]
Jose JM, De Ungria MCA.
europepmc +1 more source

