Results 21 to 30 of about 318,926 (310)

Saikosaponin D improves chemosensitivity of glioblastoma by reducing the its stemness maintenance

Biochemistry and Biophysics Reports, 2022
Objective: Chemotherapy is one of the important adjuvant methods for the treatment of glioblastoma (GBM), and chemotherapy resistance is a clinical problem that neurooncologists need to solve urgently.
Jin Liang, Jing Sun, Aibin Liu, Lei Chen, Xiaofang Ma, Xiaozhi Liu, Chunyan Zhang   +6 more
doaj   +1 more source

A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

BMC Medicine, 2023
Background Preterm birth (PTB), defined as delivery before 37 gestational weeks, imposes significant public health burdens. A recent maternal genome-wide association study of spontaneous PTB identified a noncoding locus near the angiotensin II receptor ...
Li Wang, Robert M. Rossi, Xiaoting Chen, Jing Chen, Jilian Runyon, Mehak Chawla, Daniel Miller, Carmy Forney, Arthur Lynch, Xuzhe Zhang, Fansheng Kong, Bo Jacobsson, Leah C. Kottyan, Matthew T. Weirauch, Ge Zhang, Louis J. Muglia   +15 more
doaj   +1 more source

LINC00586 Represses ASXL1 Expression Thus Inducing Epithelial-To-Mesenchymal Transition of Colorectal Cancer Cells Through LSD1-Mediated H3K4me2 Demethylation

Frontiers in Pharmacology, 2022
Colorectal cancer (CRC) is a major public health problem on a global scale by virtue of its relatively high incidence. The transition of tumor cells from an epithelial to a mesenchymal-like phenotype, so-called epithelial-to-mesenchymal transition (EMT),
Fengting Liu, Xiaofang Ma, Xiaofang Ma, Xiyun Bian, Xiyun Bian, Chunyan Zhang, Chunyan Zhang, Xiaozhi Liu, Xiaozhi Liu, Qiang Liu   +9 more
doaj   +1 more source

15-Deoxy-Delta-12,14-prostaglandin J2 modulates pro-labour and pro-inflammatory responses in human myocytes, vaginal and amnion epithelial cells

Frontiers in Endocrinology, 2022
BackgroundPrematurity is the leading cause of childhood death under the age of five. The aetiology of preterm birth is multifactorial; however, inflammation and infection are the most common causal factors, supporting a potential role for ...
Zahirrah BM. Rasheed, Zahirrah BM. Rasheed, Yun S. Lee, Yun S. Lee, Sung H. Kim, Sung H. Kim, Tg Teoh, Tg Teoh, Tg Teoh, David A. MacIntyre, David A. MacIntyre, Phillip R. Bennett, Phillip R. Bennett, Lynne Sykes, Lynne Sykes, Lynne Sykes   +15 more
doaj   +1 more source

Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study

American Journal of Perinatology Reports, 2021
Objective The aim of the study is to evaluate the risk of preterm birth (PTB,
Rebecca J. Baer, Nichole Nidey, Gretchen Bandoli, Brittany D. Chambers, Christina D. Chambers, Sky Feuer, Deborah Karasek, Scott P. Oltman, Larry Rand, Kelli K. Ryckman, Laura L. Jelliffe-Pawlowski   +10 more
doaj   +1 more source

Adverse Pregnancy Outcomes by Degree of Maternal Serum Analyte Elevation: A Retrospective Cohort Study

American Journal of Perinatology Reports, 2020
Objective The aim of this study was to evaluate rates of preterm birth (PTB) and obstetric complication with maternal serum analytes > 2.5 multiples of the median (MoM) by degree of elevation.
Amanda Yeaton-Massey, Rebecca J. Baer, Larry Rand, Laura L. Jelliffe-Pawlowski, Deirdre J. Lyell   +4 more
doaj   +1 more source

Preventing preterm births: analysis of trends and potential reductions with interventions in 39 countries with very high human development index. [PDF]

, 2013
BACKGROUND: Every year, 1·1 million babies die from prematurity, and many survivors are disabled. Worldwide, 15 million babies are born preterm (
Lackritz, Eve M, Cairns-Smith, Sarah, Chang, Hannah H, Spong, Catherine Y, Lawn, Joy E, Born Too Soon preterm prevention analysis group, Lee, Shoo K, Simpson, Joe Leigh, Howson, Christopher P, Serazin, Andrew C, Mason, Elizabeth, Walani, Salimah, Blencowe, Hannah, Larson, Jim   +13 more
core   +1 more source

Conceptualizing pathways linking women’s empowerment and prematurity in developing countries

BMC Pregnancy and Childbirth, 2017
Background Globally, prematurity is the leading cause of death in children under the age of 5. Many efforts have focused on clinical approaches to improve the survival of premature babies. There is a need, however, to explore psychosocial, sociocultural,
Patience A. Afulani, Molly Altman, Joseph Musana, May Sudhinaraset   +3 more
doaj   +1 more source

Preterm labor

Clinics in Perinatology, 1982
Clinics in Perinatology 30 (2003) xi-xii. doi:10.1016/S0095-5108(03)00113-1 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:21:10 ; DOI:10.1016/S0095-5108(03)00113-1 ; Page Range: xi ...
Department of Obstetrics and Gynecology, University of Florida Health Sciences Center/Jacksonville W. 8 th Street, Jacksonville, FL 32209, USA ( host institution ), Huddleston, John F. ( author )   +1 more
openaire   +3 more sources

Differing Prevalence and Diversity of Bacterial Species in Fetal Membranes from Very Preterm and Term Labor [PDF]

, 2009
Background: Intrauterine infection may play a role in preterm delivery due to spontaneous preterm labor (PTL) and preterm prolonged rupture of membranes (PPROM). Because bacteria previously associated with preterm delivery are often difficult to culture,
Malika Azizia, Nigel Klein, Kathryn A Harris, Donald Peebles, Hannah E Jones, Hartley, JC, John C Hartley, Lindsay Bank, Jones, HE, Peebles, D, Bernadette Carpenter, Harris, KA, Azizia, M, Carpenter, B, Bank, L, Klein, N   +15 more
core   +1 more source