Results 121 to 130 of about 1,762,642 (311)

Preterm birth recurrence after spontaneous preterm birth between 16-28 weeks: A national cohort study

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Objective: To assess the risk of recurrent preterm birth following spontaneous extreme preterm birth between 16+0 - 27+6 weeks. Methods: A nationwide retrospective cohort study was conducted with data from the Perinatal Registry of the Netherlands.
Annabelle L. Van Gils, Anita C. Ravelli, Esmé I. Kamphuis, Brenda M. Kazemier, Eva Pajkrt, Martijn A. Oudijk, Marjon A. De Boer   +6 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Massive ascites complicating preeclampsia: an indication for preterm birth?

, 2005
We report rare cases of massive maternal ascites complicating severe pre-eclamptic toxemia. This complication developed in association with the rise of blood pressure to 160/110 mmHg or more, worsening of proteinuria and hyperuricemia.
RAFFAELLI, Ricciarda, PADOVANI, Ezio Maria, Cromi A, PAPADOPOULOS, Nikolaos, Raspaolo V, Musola M, Bergamini V, FRANCHI, Massimo Piergiuseppe   +7 more
core   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Protein networks are influenced by maternal BMI and differentiate preterm birth types

Communications Medicine
Background Preterm birth remains a leading cause of neonatal morbidity and mortality. It is classified as spontaneous, characterized by the unexpected onset of labor, or medically indicated, resulting from obstetric intervention due to pregnancy ...
Paola A. Lopez Zapana, Chelsea A. DeBolt, Luka Karginov, Valerie Riis, Liqhwa Ncube, Andrea G. Edlow, Michal A. Elovitz, Douglas A. Lauffenburger   +7 more
doaj   +1 more source

Trends and predictors of extreme preterm birth: Western Australian population-based cohort study.

PLoS ONE, 2019
BACKGROUND:The preterm birth rate is rising in high-income countries and is associated with increased mortality and morbidity. Although the risks increase with greater prematurity and risk factors have been found to vary with gestational age and labour ...
Brad M Farrant, Scott W White, Carrington C J Shepherd   +2 more
doaj   +1 more source

Prevalence and risk factors for low birth weight in Ardabil, Iran. [PDF]

Introduction: Low birth weight (LBW) is the most common cause of neonatal death in developing countries. The objective of our study was to determine the prevalence and risk factors associated with low birth weight in Ardabil, Iranfrom 2010 to 2011 ...
حضرتی, صادق, احمدی هادی, پیمانه, میرزا رحیمی, مهرداد, عالی جهان, راحله   +3 more
core  

Preterm birth.

, 2017
Preterm birth.
Sakthivel Govindaraj (3768901), Annadurai Shanmuganathan (3768907), Ravindran Rajan (3768904)   +2 more
core   +1 more source

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source