Results 201 to 210 of about 159,532 (315)

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the ...
Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M. T. Sherwin, Anne van Rongen, Daniëlla W. E. Roofthooft, Sinno H. P. Simons, Dick Tibboel, Robert B. Flint, John N. van den Anker, Catherijne A. J. Knibbe   +11 more
wiley   +1 more source

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

The Journal of Clinical Pharmacology, EarlyView.
Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior, Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood   +4 more
wiley   +1 more source

The Effect of Probiotics on Preterm Birth Rates in Pregnant Women After a Threatened Preterm Birth Episode (The PROPEV Trial). [PDF]

Biomedicines
Del Barco E, Molano LG, Vargas M, Miserachs M, Puerto L, Garrido-Giménez C, Soler Z, Muñoz B, Pratcorona L, Rimbaut S, Vidal M, Dalmau M, Casellas A, Carreras E, Manichanh C, Goya M.   +15 more
europepmc   +1 more source

Assessing cognition in autistic youth with and without attention‐deficit/hyperactivity disorder using the NIH Toolbox Cognition Battery: An Environmental influences on Child Health Outcomes‐Wide Cohort Study

JCPP Advances, EarlyView.
Autistic individuals tend to experience difficulties with fluid cognition as found previously, with minimal impact of ADHD. However, there was a notable proportion of autistic individuals with average or superior cognitive performance, highlighting the importance of strength‐based and transdiagnostic research approaches.
Catrina A. Calub, Aisha S. Dickerson, Haozuo Zhao, Robert M. Joseph, Michael O'Shea, Shaikh I. Ahmad, Lisa A. Croen, Sean C. L. Deoni, Viren A. D’Sa, Akhgar Ghassabian, Daphne Koinis‐Mitchell, Leonardo Trasande, Heather Volk, Anna J. Yeo, Irva Hertz‐Picciotto, Julie B. Schweitzer, Marjorie Solomon, for the ECHO Cohort Consortium   +17 more
wiley   +1 more source

Keeping it simple: lung imaging of alveolar simplification in preterm-birth children. [PDF]

ERJ Open Res
Matheson AM, Parraga G.
europepmc   +1 more source

Morbidity and Mortality of Preterm Twins and Higher-Order Multiple Births

, 2001
Kirin N. Suri, Vineet Bhandari, Trudy Lerer, Ted S. Rosenkrantz, Naveed Hussain   +4 more
openalex   +1 more source

Grandmother's pregnancy complications and autism spectrum disorders in grandchildren, a California multigenerational cohort study

JCPP Advances, EarlyView.
Abstract Background Pregnancy complications have been associated with offspring autism spectrum disorders (ASD). There has also been increasing evidence for multigenerational risk factors of ASD. Methods In a multigenerational California birth cohort of 1,740,379 mother–child pairs, we investigated pregnancy complications when the grandmother was ...
Ting Chow, Qi Meng, Jingyuan Xiao, Karl O’Sharkey, Zeyan Liew, Beate Ritz   +5 more
wiley   +1 more source

The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications. [PDF]

Front Cell Dev Biol
Meng L, Yang J, Gao Y, Xie Y, Chen M, Hao W, Luo Y, Ru P, Wang L, He Z, Liu M.   +10 more
europepmc   +1 more source