Results 61 to 70 of about 207,214 (306)

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Opium use during pregnancy and risk of preterm delivery: A population-based cohort study.

PLoS ONE, 2017
BackgroundUse of narcotic or "recreational" drugs has been associated with adverse pregnancy outcomes such as preterm delivery. However, the associations might be confounded by other factors related to high-risk behaviours.
Siavash Maghsoudlou, Sven Cnattingius, Scott Montgomery, Mohsen Aarabi, Shahriar Semnani, Anna-Karin Wikström, Shahram Bahmanyar   +6 more
doaj   +1 more source

The increasing trend in preterm birth in public hospitals in northern Argentina [PDF]

, 2015
Objective: To identify factors associated with the increasing incidence of preterm birth in northern Argentina. Methods: In an observational study, data were reviewed from a prospective, population-based registry of pregnancy outcomes in six cities in ...
Althabe, Ananth, Argentina National Ministry of Health, Argentina National Ministry of Health, Bassil, Black, Blencowe, Blondel, Chang, Emily H. Weaver, Fernando Althabe, Goudar, Gravett, Joseph, José M. Belizán, Kramer, Kuehn, Langhoff-Roos, Lawn, Lopez, Luz Gibbons, Norman, Victora   +22 more
core   +2 more sources

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Practice patterns in the administration of late preterm antenatal corticosteroidsAJOG Global Reports at a Glance

AJOG Global Reports, 2021
BACKGROUND: Given the unpredictable nature of preterm birth and the short-term impact of antenatal corticosteroids on neonatal outcomes, optimal timing of antenatal corticosteroid administration (2–7 days from expected birth) remains challenging ...
Moti Gulersen, MD, MSc, Cynthia Gyamfi-Bannerman, MD, MSc, Michelle Greenman, MD, Erez Lenchner, PhD, Burton Rochelson, MD, Eran Bornstein, MD   +5 more
doaj   +1 more source

Maternal Contributions to Preterm Delivery [PDF]

American Journal of Epidemiology, 2009
Preterm delivery (PTD) is a complex trait with a significant familial component. However, no specific inheritance patterns have been established. The authors examined the contribution of PTDs in both the woman's family and her partner's family to her risk of PTD.
Heather A, Boyd, Gry, Poulsen, Jan, Wohlfahrt, Jeffrey C, Murray, Bjarke, Feenstra, Mads, Melbye   +5 more
openaire   +2 more sources

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Raised electrical uterine activity and shortened cervical length could predict preterm delivery in a low-risk population [PDF]

, 2012
PURPOSE: To compare diagnostic accuracy of sonographic cervical length (CL) measurement and uterine electric activity assessed by electromyography (EMG) in second trimester regarding prediction of preterm delivery (PTD).
Grgić, Ozren, Kuna, Krunoslav, Matijević, Ratko   +2 more
core   +1 more source

Histologic Chorioamnionitis and Preterm Delivery [PDF]

American Journal of Epidemiology, 2007
Inconsistent findings linking placental histologic chorioamnionitis (HCA) and preterm delivery may result from variations in HCA definition, population studied, and exclusion criteria. This analysis from the 1998-2004 Pregnancy Outcomes and Community Health Study (five Michigan communities) includes the first 1,053 subcohort women (239 preterm, 814 ...
Claudia, Holzman, Ximin, Lin, Patricia, Senagore, Hwan, Chung   +3 more
openaire   +2 more sources

Recurrent preterm delivery following twin versus singleton preterm delivery: A retrospective cohort

International Journal of Gynecology & Obstetrics, 2023
AbstractObjectiveThe main risk factor for preterm delivery (PTD; <37 gestational weeks) is having a history of PTD. The aim of this research was to compare the risk for recurrent PTD following twin versus singleton gestation PTD.MethodsA retrospective population‐based cohort study was performed, including all women who had two consecutive ...
Tamar Wainstock, Ilana Shoham‐Vardi, Ruslan Sergienko, Eyal Sheiner   +3 more
openaire   +2 more sources