Results 191 to 200 of about 1,165,802 (378)

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates   +26 more
wiley   +1 more source

Impact of changes in cellular bioactive substances of amniotic fluid on the development of fetal growth restriction and preterm labor

open access: bronze, 2017
N. A. Drukker   +6 more
openalex   +1 more source

Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomics [PDF]

open access: yes, 2016
Bennett, PR   +9 more
core   +1 more source

Constraints and Frugal Innovation: Enabling Sustainable Production Through the New Product Development Process

open access: yesSustainable Development, EarlyView.
ABSTRACT This paper advances understanding of how constraint‐based thinking fosters sustainable innovation under resource limitations. Based on five case studies of small and medium‐sized enterprises and research groups developing frugal medical devices across diverse regions, it identifies how market, infrastructure, and user constraints shape design ...
Zulfiya Ukbaeva   +2 more
wiley   +1 more source

Mono(2‐Ethylhexyl) Phthalate Induces Inflammatory and Angiogenic Alterations Mediated by the PI3K/AKT Pathway in HTR‐8/SVneo Trophoblastic Cells

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo   +5 more
wiley   +1 more source

Umbilical cord CD71+ erythroid cells are reduced in neonates born to women in spontaneous preterm labor

open access: green, 2016
Nardhy Gomez‐Lopez   +7 more
openalex   +2 more sources

Oral misoprostol (PGE1) vs vaginal dinoprostone (PGE2) for labor induction: individual participant data meta‐analysis of randomized controlled trials

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of oral misoprostol vs vaginal dinoprostone for the induction of labor (IOL) using an individual participant data (IPD) meta‐analysis. Methods We used a Cochrane review and searched Ovid MEDLINE, Ovid Embase, Ovid Emcare, CINAHL Plus, Scopus and ClinicalTrials.gov to identify randomized ...
S. Y. Tan   +13 more
wiley   +1 more source

Relation between Home Work and Preterm Labor

open access: yesحیات, 2012
Background & Aim: Preterm birth is the main cause of neonatal mortality and morbidity; so, prevention of preterm labor is a priority in health care. This study aimed to determine relationship between house works with preterm labor.
Nahid Mehran   +3 more
doaj  

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