Results 41 to 50 of about 86,301 (354)

Activation of the epithelial sodium channel (ENaC) leads to cytokine profile shift to pro‐inflammatory in labor

EMBO Molecular Medicine, 2018
The shift of cytokine profile from anti‐ to pro‐inflammatory is the most recognizable sign of labor, although the underlying mechanism remains elusive. Here, we report that the epithelial sodium channel (ENaC) is upregulated and activated in the uterus ...
Xiao Sun, Jing Hui Guo, Dan Zhang, Jun‐jiang Chen, Wei Yin Lin, Yun Huang, Hui Chen, Wen Qing Huang, Yifeng Liu, Lai Ling Tsang, Mei Kuen Yu, Yiu Wa Chung, Xiaohua Jiang, Hefeng Huang, Hsiao Chang Chan, Ye Chun Ruan   +15 more
doaj   +1 more source

Resolving the Uncertainty of Preterm Symptoms: Women’s Experiences With the Onset of Preterm Labor [PDF]

, 2002
Objective: To describe expectant women\u27s experiences with the onset of preterm labor. Design: Qualitative, using grounded theory methods. Setting: Southwestern tertiary women\u27s hospital.
Harris, Susan, Saks, Nancy P, Weiss, Marianne E.   +2 more
core   +1 more source

Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interface. [PDF]

, 2017
BackgroundPreterm birth is a main determinant of neonatal mortality and morbidity and a major contributor to the overall mortality and burden of disease.
Andrews, William, Baldwin, Donald A, Biggio, Joseph R, Bukowski, Radek, Esplin, Sean M, Goodarzi, Hani, Ilekis, John V, Parry, Samuel, Reddy, Uma M, Saade, George R, Sadovsky, Yoel, Varner, Michael, Xiao, Feifei, Zhang, Heping   +13 more
core   +2 more sources

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

The Association Between Advanced Maternal Age and Short Interpregnancy Intervals on Preterm Labor [PDF]

, 2019
Background: Preterm birth is the leading cause of neonatal and infant mortality and has become a major health concern due to the increasing rates of infant deaths in the United States (WHO, 2017). Studying maternal risk factors for preterm labor provides
Burns, Hannah N., DuChanois, Kristi L.
core   +1 more source

Metabolomics application in maternal-fetal medicine [PDF]

, 2013
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L, Fanos, V, Ferrazzi, E, Makarenko, K, Melis, GB   +4 more
core   +4 more sources

Large‐Scale Production of Transfusion‐Ready Red Blood Cells From Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
A scalable, dynamic culture system is developed to produce red blood cells from induced pluripotent stem cells. It achieves high yields with up to 70% enucleation, not previously shown in dynamic systems, overcoming key limitations and enabling large‐scale production.
Eszter Varga, Eelke Brandsma, Brenda E. Juarez‐Garza, Renuka P. E. Ramlal, Julien J. Karrich, Adrien Laurent, Athina Chavli, Ruthmila Paskel, Kerly Fu, Richard A. Flavell, Marieke von Lindern, Derk Amsen, Marieke E. Klijn, Emile van den Akker   +13 more
wiley   +1 more source

Risk factors associated with preterm labor in young mothers assisted in a hospital of Peru

Medisan, 2021
Introduction: Preterm labor is one of the main causes of neonatal morbidity and mortality whose origin is associated with the presence and interaction of factors related to the mother and her environment.
Rocio Huarcaya-Gutierrez, Mayra Cerda-Sanchez, John Barja-Ore   +2 more
doaj  

TRPC3 Overexpression Promotes the Progression of Inflammation-Induced Preterm Labor and Inhibits T Cell Activation

Cellular Physiology and Biochemistry, 2018
Background/Aims: To detect the expression of the TRPC3 channel protein in the tissues of women experiencing preterm labor and investigate its interaction with T lymphocytes, providing a theoretical basis for the clinical prevention of threatened preterm ...
Chen Jing, Zheng Dongming, Cui Hong, Na Quan, Liu Sishi, Liu Caixia   +5 more
doaj   +1 more source

Differences in Inflammatory Markers between Nulliparous Women Admitted to Hospitals in Preactive vs Active Labor [PDF]

, 2015
Objective To determine whether labor-associated inflammatory markers differ between low-risk, nulliparous women in preactive vs active labor at hospital admission and over time.
Arntzen, Bailit, Banchereau, Bennett, Bennett, Bollapragada, Caughey, Donna O. McCarthy, Golightly, Gotsch, Greig, Gucer, Hamilton, Hebisch, Holm, Holmes, Impey, Jane M. Lamp, Jarocki, Jeremy L. Neal, Kumar, Lin, Loraine T. Sinnott, Mikolajczyk, Mitchell, Nancy K. Lowe, Neal, Neal, Norman, Nowak, Nowak, Opsjln, Osman, Osmers, Papatheodorou, Ragusa, Rahnama, Roh, Romero, Sennstrom, Shannon L. Gillespie, Shynlova, Thomson, Torbe, Tribe, Vitoratos, Vitoratos, Young, Yuan, Zhang, Zhang   +50 more
core   +2 more sources