Myocardial and Arrhythmic Spectrum of Neuromuscular Disorders in Children
Neuromuscular disorders (NMDs) are highly heterogenous from both an etiological and clinical point of view. Their signs and symptoms are often multisystemic, with frequent cardiac involvement.
Anwar Baban+8 more
doaj +1 more source
Lamin A/C (LMNA) encodes for two nuclear intermediate filament proteins. Mutations in LMNA cause a highly heterogeneous group of diseases predominantly leading to muscular or cardiac disease, lipodystrophy syndromes, peripheral neuropathy, and ...
Anwar Baban+10 more
doaj +1 more source
Association Between Neighborhood Factors and Adult Obesity in Shelby County, Tennessee: Geospatial Machine Learning Approach [PDF]
Obesity is a global epidemic causing at least 2.8 million deaths per year. This complex disease is associated with significant socioeconomic burden, reduced work productivity, unemployment, and other social determinants of Health (SDoH) disparities.
arxiv +1 more source
Tapering of biological treatment in autoinflammatory diseases: a scoping review
Background Biological treatment and treat-to-target approaches guide the achievement of inactive disease and clinical remission in Autoinflammatory Diseases (AID).
Tatjana Welzel+5 more
doaj +1 more source
Vitronectin-based hydrogels recapitulate neuroblastoma growth conditions
The tumor microenvironment plays an important role in cancer development and the use of 3D in vitro systems that decouple different elements of this microenvironment is critical for the study of cancer progression. In neuroblastoma (NB), vitronectin (VN),
Ezequiel Monferrer+9 more
doaj +1 more source
Introduction: The epidemiologic characteristics of erectile dysfunction (ED) in mainland China remain incompletely understood. Aim: To evaluate the overall prevalence and determine the severity of ED in mainland China.
Wenying Wang, MD, PhD+6 more
doaj +1 more source
Characterization of cardiac involvement in children with LMNA-related muscular dystrophy
Introduction: LMNA-related muscular dystrophy is a rare entity that produce “laminopathies” such as Emery–Dreifuss muscular dystrophy (EDMD), limb–girdle muscular dystrophy type 1B (LGMD1B), and LMNA-related congenital muscular dystrophy (L-CMD).
Sergi Cesar+47 more
doaj +1 more source
Using Deep Learning to Examine the Association between the Built Environment and Neighborhood Adult Obesity Prevalence [PDF]
More than one-third of the adult population in the United States is obese. Obesity has been linked to factors such as, genetics, diet, physical activity and the environment. However, evidence indicating associations between the built environment and obesity has varied across studies and geographical contexts.
arxiv +1 more source
Prevalence and Associated Factors of Metabolic Syndrome and Its Individual Components Among Adolescents [PDF]
Metabolic syndrome is a growing health problem that affects the whole population including adolescents due to change in lifestyles. It is strongly associated with different lifestyle behavioral factors.
Bekel, G. E. (Getabalew)+1 more
core
Standardising Care and Treatment of Transthyretin Amyloid Cardiomyopathy
Transthyretin cardiac amyloidosis (ATTR-CA) has been traditionally considered a rare and inexorably fatal condition. ATTR-CA now is an increasingly recognised cause of heart failure and mortality worldwide with effective pharmacological treatments ...
Marianna Fontana+2 more
doaj +1 more source