Global burden of colistin-resistant bacteria : mobilized colistin resistance genes study (1980-2018) [PDF]
Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The recent global dissemination of mobilized colistin resistance (mcr) genes is an urgent public health threat.
Elbediwi, Mohammed +10 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Cardiac Rehabilitation for Fontan Circulation Patients: A Systematic Review, and Meta-Analysis
Background and Objectives: Despite advances in the surgical management of patients with Fontan circulation, their exercise capacity and quality of life remain significantly impaired.
Luna van de Ven +5 more
doaj +1 more source
Prevalence of internet addiction disorder in Chinese university students: A comprehensive meta-analysis of observational studies [PDF]
Background and aims: Internet addiction disorder (IAD) is common in university students. A number of studies have examined the prevalence of IAD in Chinese university students, but the results have been inconsistent.
Chai, Jing-Xin +10 more
core +3 more sources
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Prevalence of intestinal parasitic infections among university female students, Gaza, Palestine [PDF]
The intestinal parasites are still endemic among children, women, and men in Gaza Strip. To the best of our knowledge, this is the first study of intestinal parasites among young female students of Islamic University of Gaza to report the existence and ...
Abu Qassem, RR +4 more
core +2 more sources
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Freshwater snails as the intermediate host of trematodes in Iran: a systematic review [PDF]
Freshwater snails, as the first intermediate hosts of trematodes, can cause health hazards in animals and humans. Recently, the World Health Organization has included Iran in a list of 6 countries known to have serious problems with fascioliasis.
Samira Dodangeh +6 more
doaj +1 more source
Accounting for recent trends in the prevalence of diarrhoea in the Democratic Republic of Congo (DRC) : results from consecutive cross-sectional surveys [PDF]
Objectives: To analyse trends in diarrhoea prevalence by maternal education, access to clean water and improved sanitation, household wealth index; to identify the sources of variation and assess contribution of changes in socioeconomic characteristics ...
Emina Be-Ofuriyua, Jacques +1 more
core +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source

