Results 101 to 110 of about 1,654,926 (292)

Prevalence of Lens Opacities in India: The INDEYE Study [PDF]

open access: yes, 2008
PurposeTo describe the prevalence of lens opacities in older people in India. MethodsPeople aged 60 years and older identified using random cluster-sampling in 2 study centres in north and south India, attended an eye examination.
Ravindran, RD   +9 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Prevalence rates for constipation and faecal and urinary incontinence [PDF]

open access: yesArchives of Disease in Childhood, 2007
To evaluate the prevalence rates for constipation and faecal and urinary incontinence in children attending primary care clinics in the United States.Retrospective review of case records of all children, 4-17 years of age, seen for at least one health maintenance visit during a 6 month period and followed from birth or within the first 6 months of age ...
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Specific Age and Gender Prevalence of Hepatitis C Virus Infection in Iran [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Mohammad Saeid Rezaee-Zavareh   +1 more
doaj   +1 more source

Mental health and help-seeking in Czech sexual minorities: a nationally representative cross-sectional study

open access: yesEpidemiology and Psychiatric Sciences
Aims The mental health of sexual minority (SM) individuals remains overlooked and understudied in Czechia. We aimed to estimate (1) the prevalence rate and (2) the relative risk of common mental disorders and (3) the mental distress severity among the ...
Michal Pitoňák   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Internal evaluation of national leprosy elimination program in tribal Gujarat

open access: yesIndian Journal of Community Medicine, 2010
Background: The government launched a National Leprosy Eradication program in 1983, to eliminate leprosy from India. A Modified Leprosy Elimination Campaign was started with the view to early case detection and treatment.
Singh Anjali
doaj  

Association of exposure duration, modality, and polycythaemia with hyperuricaemia among han male immigrants at high altitudes: a cross-sectional study

open access: yesAnnals of Medicine
Background Hyperuricaemia is associated with increased metabolic syndrome, cardiovascular disease, and mortality risk in the adult population and is more common in plateau areas.
Yanlin Zhu   +9 more
doaj   +1 more source

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