Results 71 to 80 of about 13,680,867 (312)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017

open access: yesNature, 2019
HIV/AIDS is a leading cause of disease burden in sub-Saharan Africa. Existing evidence has demonstrated that there is substantial local variation in the prevalence of HIV; however, subnational variation has not been investigated at a high spatial ...
L. Dwyer-Lindgren   +40 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Legg–Calve–Perthes Disease

open access: yesВопросы современной педиатрии, 2015
Legg–Calve–Perthes disease is a form of femur and hip joint pathology that belongs to the osteochondropathy group. The disease is caused by disorders of blood circulation and nutrition of articular cartilage leading to necrosis of the femoral head.
N. Yu. Krutikova, A. G. Vinogradova
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Incidence and Risk Factors of Post-Operative Depression in Patients Undergoing Transurethral Resection of Prostate for Benign Prostatic Hyperplasia

open access: yesInternational Journal of General Medicine, 2021
Daofang Zhu,1 Jingjing Gao,1 Xianming Dou,2 Dangwei Peng,1 Yao Zhang,1 Xiansheng Zhang1 1Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, People’s Republic of China; 2Department of Urology, Anhui No.
Zhu D   +5 more
doaj  

Time trends of HBeAg prevalence rate.

open access: yesKanzo, 1986
わが国のHBVキャリアにおけるHBe抗原陽性率の年次推移を明らかにするために,年齢階級別,出生コーホート別に観察した.1) 1977年1月から84年3月の間に,大阪府赤十字血液センターが取扱ったHBs抗原陽性の献血者,男23,560人,女8,659人を調査対象とした.2) 性,年齢階級別にHBe抗原陽性率の年次推移を観察すると,男女とも近年HBe抗原陽性率が低下しつつあったが,特に,10歳代,20歳代でその傾向が著しかった.3) HBe抗原陽性率は,年齢とともに低下したが,同じ年齢階級でも出生年代が若くなるにつれて,HBe抗原陽性率は低くなった.4) 以上から,わが国のHBVキャリアにおけるHBe抗原陽性率は,今後も低下傾向を持続すると推測された.
Hideaki TSUKUMA   +4 more
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Distribution and Size of Barnacle Chelonibia patula Fouling Blue Crab Callinectes amnicola in Southeast Nigeria

open access: yesCroatian Journal of Fisheries, 2016
The distribution and occurrence of epibionts on the dorsal carapace, ventral carapace and chela of 325 specimens of Callinectes amnicola (De Rocheburne, 1883) (103.4 - 138.7 mm carapace width) from the Qua Iboe (QIRE) and Imo River (IRE) estuaries in ...
Udoh James Philip, Otoh Aniekan Johnny
doaj   +1 more source

Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2016

open access: yesCancer research and treatment : official journal of Korean Cancer Association, 2019
Purpose This study presents the 2016 nationwide cancer statistics in Korea, including cancer incidence, survival, prevalence, and mortality. Materials and Methods Cancer incidence data from 1999 to 2016 were obtained from the Korea National Cancer ...
K. Jung, Y. Won, H. Kong, E. Lee
semanticscholar   +1 more source

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