Results 1 to 10 of about 5,134 (105)

Post Vaccine Rubella During a Measles Outbreak: Clinical Case

Acta Médica Portuguesa, 2021
Rubella is a vaccine preventable infection, and congenital rubella the most feared complication of this disease. Although young adult women are at greatest risk of post-vaccine rubella, this is also the group who potentially benefits the most from ...
Luísa Graça, Sara Pereira, Raquel Duro, António Sarmento   +3 more
doaj   +1 more source

Are we PREPAREd? Concerning the “PREemptive Pharmacogenomics Testing for Preventing Adverse Drug Reactions (PREPARE) Study”

Acta Médica Portuguesa, 2023
N/a.
Ana de Carmo Campos, Maria Luís Cardoso, Astrid Vicente   +2 more
doaj   +1 more source

Characterization of Two Variants at Met 1 of the Human LDLR Gene Encoding the Same Amino Acid but Causing Different Functional Phenotypes

Biomedicines, 2021
Familial hypercholesterolemia (FH) is the most common genetic disorder of lipid metabolism, characterized by increased levels of total and LDL plasma cholesterol, which leads to premature atherosclerosis and coronary heart disease.
Rafael Graça, Rafael Fernandes, Ana Catarina Alves, Juliane Menezes, Luísa Romão, Mafalda Bourbon   +5 more
doaj   +1 more source

Performance comparison of different classification algorithms applied to the diagnosis of familial hypercholesterolemia in paediatric subjects

Scientific Reports, 2022
Familial Hypercholesterolemia (FH) is an inherited disorder of lipid metabolism, characterized by increased low density lipoprotein cholesterol (LDLc) levels.
João Albuquerque, Ana Margarida Medeiros, Ana Catarina Alves, Mafalda Bourbon, Marília Antunes   +4 more
doaj   +1 more source

Biomedical knowledge graph embeddings for personalized medicine: Predicting disease‐gene associations

Expert Systems, Volume 40, Issue 5, June 2023., 2023
Abstract Personalized medicine is a concept that has been subject of increasing interest in medical research and practice in the last few years. However, significant challenges stand in the way of practical implementations, namely in regard to extracting clinically valuable insights from the vast amount of biomedical knowledge generated in the last few
Joana Vilela, Muhammad Asif, Ana Rita Marques, João Xavier Santos, Célia Rasga, Astrid Vicente, Hugo Martiniano   +6 more
wiley   +1 more source

The efficacy of subcutaneous slow‐release melatonin implants in the prevention of canine flank alopecia recurrence is uncertain: A double‐blind, randomized, placebo‐controlled study

Veterinary Dermatology, Volume 33, Issue 6, Page 553-558, December 2022., 2022
Background – Canine flank alopecia (CFA) is characterized by seasonally recurring noninflammatory, occasionally hyperpigmented alopecia predominantly in the thoracolumbar area. Previous studies suggest that reduced production of endogenous melatonin may play a role in the pathogenesis of this condition, and placebo‐controlled studies on the efficacy of
Millie U. M. Y. Verschuuren, Yvette M. Schlotter, Inge M. van Geijlswijk, Jaco J. van der Lugt, Ronette Gehring   +4 more
wiley   +1 more source

High-Throughput Microscopy Characterization of Rare LDLR Variants

JACC: Basic to Translational Science, 2023
Summary: Familial hypercholesterolemia (FH) is the most common inherited life-threatening disorder of lipid metabolism. Early diagnosis and treatment are the key to reduce the cumulative life-long cardiovascular burden of patients with FH.
Rafael Graça, MSc, Magdalena Zimon, PhD, Ana C. Alves, PhD, Rainer Pepperkok, PhD, Mafalda Bourbon, PhD   +4 more
doaj   +1 more source

Prevention and management of respiratory disease in young people with cerebral palsy: consensus statement

Developmental Medicine &Child Neurology, Volume 63, Issue 2, Page 172-182, February 2021., 2021
Respiratory illness is the leading cause of mortality in children with cerebral palsy (CP). Although risk factors for developing chronic respiratory illness have been identified, comprehensive clinical care recommendations for the prevention and management of respiratory illness do not currently exist.
Noula Gibson, Amanda M Blackmore, Anne B Chang, Monica S Cooper, Adam Jaffe, Wee‐Ren Kong, Katherine Langdon, Lisa Moshovis, Karolina Pavleski, Andrew C Wilson   +9 more
wiley   +1 more source

Ação extensionista de promoção da saúde e prevenção de doenças cardiovasculares para alunos de uma escola da Bahia

Extensio: Revista Eletrônica de Extensão, 2021
Objetivo: Relatar a experiência de uma ação educativa sobre prevenção de doenças relacionadas aos hábitos de vida realizada em uma escola no Extremo Sul da Bahia. Método: Foram realizados 3 encontros de 4 horas, com 76 estudantes do nono ano.
Aline Prates Correia, Fábio Jambeiro Santana Borges, Karolina de Oliveira Lima, Kawan Moreira Santana, Laila Cheibub Costa Rodrigues, Grasiely Faccin Borges   +5 more
doaj   +1 more source

Epidemiology of Clostridioides difficile Infection in Portugal: A Retrospective, Observational Study of Hospitalized Patients

Acta Médica Portuguesa, 2022
Introduction: Clostridioides difficile is the main cause of healthcare-associated diarrhea in Europe and North America. The aim of this study was to characterize the epidemiology and clinical burden of Clostridioides difficile infection among ...
Cláudia Nazareth, Inês Leitão, Ernestina Reis, Hugo Inácio, Filomena Martins, Elmano Ramalheira, Flávia Cunha, Carla Santos, Sara Lino, Hugo Moreira, Nadiya Kruptsala, Andrea Santos, Laura Paixão, Leonor Pássaro, Mónica Oleastro   +14 more
doaj   +1 more source