Results 121 to 130 of about 7,991,089 (298)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Planning a programme to prevent visual loss from diabetic retinopathy [PDF]

open access: yes, 2015
Diabetes mellitus is increasing, so it is relevant to plan services to prevent vision loss from diabetic ...
Foster, Allen, Allen Foster
core  

Barbarous Custom: discursively deconstructing The Prevent Duty

open access: yesEducational Futures, 2019
The contentious anti-terrorism programme for education, The Prevent Duty, designed to enable teachers, lecturers and youth workers to intervene if young people are ‘at risk’ of radicalisation, remains subject to criticism, most recently that it creates a
Kate Brooks
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

How to prevent 804,000 children under five dying

open access: yes, 2013
Exclusive breastfeeding infants until six months of age can prevent 804,000 under five deaths each year however less than 40% of infants worldwide are.
Keith, R.
core  

Preventing Electoral Fraud in Indonesia: Protecting the Social Security of Election Management Personnel

open access: yesJurnal Media Hukum
Indonesia’s Election Management Bodies (EMBs), constitutionally mandated to manage legislative and presidential elections, face substantial risks, including accidents and fatalities.
Agus Riwanto   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Protect your community, prevent wildfires. Spanish

open access: yes, 2021
Title from PDF caption (viewed on May 21, 2021).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

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