Results 221 to 230 of about 8,076,451 (351)

Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease.

JAMA Netw Open
Van't Hof JR, Duval S, Oldenburg N, Eder M, Luepker RV.   +4 more
europepmc   +1 more source

Dietary Antioxidants and Redox Signaling in Cancer Prevention: Mechanistic Insights and Metabolic Inflammation. [PDF]

Nutrients
Ispas V, Maggio V, Hassan HS, Sayilgan AI, Hassan FM, Ispas S, Rizzo M.   +6 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Assessing Evidence to Guide Primary Prevention of Pathogen X. [PDF]

Emerg Infect Dis
Holmes I, Vora NM, Gurley ES, Hassan L, Markotter W, Lloyd-Smith JO, Plowright RK.   +6 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Effectiveness of sports injury prevention programs for adolescent and children football players: a meta-analysis and systematic review. [PDF]

PeerJ
Yang H, Ding X, Fan Y, Wang X, Li JH.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Study on the effectiveness and accessibility of a CDR-based VTE quality control platform in county-level hospitals. [PDF]

BMJ Open Qual
Zang Z, Liu BS, Li J, Li L, Li Z, Liu J, Zhang J, Bian W, Yuan C, Wang M.   +9 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Application of failure mode and effects analysis combined with bundled management measures in reducing ICU-acquired infections. [PDF]

Front Med (Lausanne)
Zhang M, Ku T, Jia H, Wang Y, Zhou J, Zhang W.   +5 more
europepmc   +1 more source