Results 261 to 270 of about 6,466,594 (289)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Primary prevention implantable cardioverter-defibrillator therapy in non-ischaemic heart failure with reduced left ventricular ejection fraction: a European Heart Rhythm Association survey. [PDF]

Europace
Brociek E, Karvonen J, Mills MT, Ruwald MH, Migliore F, Conte G, Roten L, Futyma P, Marcantoni L, Mazurek M, Sultan A, Duray GZ, Perrotta L, Chun JKR.   +13 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Inflammation and suicide risk in adolescents with self-injury: Expanding the role of mental health nursing. [PDF]

World J Psychiatry
Anastasi G.
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Developing a new prevention model for pediatric respiratory infection. [PDF]

Sci Rep
Zhou J, Zhang Y, Li R, Chang YC, Peng NH.   +4 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

A Scoping Review of Family-Based Prevention Strategies in Adolescent Mental Health. [PDF]

Psychol Res Behav Manag
Widyasih H, Yunita S, Adnani QES, Arisanti N, Pandia V, Dhamayanti M.   +5 more
europepmc   +1 more source

Implementation of a short course of prophylactic antibiotic treatment for prevention of postoperative infections in clean orthopaedic surgeries

, 2013
Purva Mathur, Vivek Trikha, Kamran Farooque, Vijay K. Sharma, Neetu Jain, Nidhi Bhardwaj, Satya Priya Sharma, M C Misra   +7 more
openalex   +1 more source