Results 261 to 270 of about 8,076,451 (351)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Investigating the Implementation and Impact of AI-Assisted Fall Prevention in Hospitals: Protocol for a Multicenter, Multimethod Observational Study in Sweden (SAFE). [PDF]

JMIR Res Protoc
Siira E, Gyberg A, Larsson I, Rosenburg M, Svedberg P, Ulin K, Wijk H, Brezicka T, Hansson M, Hallgren J, Nygren J.   +10 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Status of Establishment of the Implementation Plan according to the First National Injury Prevention and Control Plan. [PDF]

Public Health Wkly Rep
Jeong J, Park J, Han S, Lee S, Jeon E.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Prevention in stroke - Current state, present gaps and probable next steps. [PDF]

Neurol Res Pract
Thielscher CS, Montellano FA, Saur D, Flöel A, Petzold GC, Haeusler KG.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mental health prevention in Poland and selected European Union member states: a comparative analysis of systemic interventions. [PDF]

Front Public Health
Weber D, Pacian A, Baryła-Matejczuk M, Kulik T, Ślifirczyk A, Strzelecka B.   +5 more
europepmc   +1 more source

Factors Influencing the Uptake of Digital Health Interventions for Cardiovascular Disease Prevention Among Healthcare Providers: A Systematic Review. [PDF]

Glob Heart
Kraselnik A, McGowan H, Amiali IA, Gibson I, Joshi S, Magero N, Miller CH, Oulousian S, Sharma A, Sonyuy MF, Kulnik ST, Shah NS.   +11 more
europepmc   +1 more source