Results 81 to 90 of about 6,274 (209)

Malaria in a metropolitan region of Southern Germany: past, present and future perspectives on a protozoan infection with the potential of re-appearance in Central Europe

Malaria Journal
Background Malaria occurred endemically in Germany until the twentieth century. Climate change and globalization are known to promote the spreading of malaria.
Jan Esse, Karl-Heinz Leven, Helge Kampen, Doreen Werner, Silke Göttler, Christian Bogdan   +5 more
doaj   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Accelerating the prioritisation of plant species with underexplored medicinal potential: The pm4mp (Phylogenetic Methods for Medicinal Plants) R package

PLANTS, PEOPLE, PLANET, EarlyView.
Medicinal plants used in ethnobotanical traditions to treat or prevent diseases have gained renewed interest for their largely untapped potential in drug discovery. In this study, we developed and tested novel methods to prioritise plant species based on their unexplored medicinal potential. By enabling researchers to target the most promising species,
Giovanni Zecca, Elisa Toini, Massimo Labra, Fabrizio Grassi   +3 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages

Pest Management Science, EarlyView.
Anopheles gambiae mosquitoes exhibit takeoff responses when presented to commercial permethrin headspace. This product elicits electrophysiological activity in the antennae and tarsi. However, only the chemical information acquired from the tarsi plays a major role in the observed behavioral response.
Sassan S Kambou, Adeline Valente, Philip Agnew, Anna Cohuet, David Carrasco   +4 more
wiley   +1 more source

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang‐Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji   +8 more
wiley   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

The Hidden Costs of Coffee Production in the Eastern African Value Chains

Sustainable Development, EarlyView.
ABSTRACT There is increasing recognition that significant hidden costs associated with agrifood systems are not reflected in market prices. Coffee is among the three most traded agricultural commodities in the world and supports the livelihoods of more than 30 million smallholder households.
Annet Adong, Lukas Kornher, Bezawit Beyene Chichaibelu, Aslihan Arslan   +3 more
wiley   +1 more source

Illegal Gold Mining in the Brazilian Amazon: Environmental Degradation in Yanomami Indigenous Lands, and Regulatory Failures

Sustainable Development, EarlyView.
ABSTRACT Illegal gold mining has emerged as a major sustainability threat in the Amazon, eroding Indigenous rights, forest integrity, and climate mitigation efforts. This study examines how international market incentives relate to the expansion of illegal mining and associated deforestation within the Yanomami Indigenous Territory (YIT) from 2008 to ...
Shirléia Lago Santos, Ana Claudia de Araujo Moxotó, Jurandir Moura Dutra   +2 more
wiley   +1 more source

The Gender of Fossil Fuels: Oil and Domestic Perils in Mandate Palestine

Gender &History, EarlyView.
ABSTRACT This article explores the gender dynamics behind the rise of kerosene – an oil derivative – as the main domestic fuel in Mandate Palestine. It argues that these dynamics were constitutive in determining who began to use oil, where and for what purposes, in turn demonstrating that women in Palestine were the promoters and targets of a campaign ...
Shira Pinhas
wiley   +1 more source