Results 91 to 100 of about 11,113,149 (315)

Reactions to extreme events: moving threshold model [PDF]

open access: yes, 2005
In spite of precautions to avoid the harmful effects of extreme events, we experience recurrently phenomena that overcome the preventive barriers. These barriers usually increase drastically right after the occurrence of such extreme events, but steadily
Altmann   +11 more
core   +4 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Audit in occupational risk prevention and occupational health: Systemic procedure applied to the Jasetrón company

open access: yesRevista Arbitrada Interdisciplinaria Koinonía, 2019
This article proposes a systemic audit procedure that reflects the faithful image of the occupational risk prevention system of Jasetrón Cía. Ltda. Located in the city of Cuenca, Ecuador.
Ana Isabel Calle Calle   +2 more
doaj   +1 more source

The impact of preventive fogging on entomological parameters in a university campus in Malaysia [PDF]

open access: yes, 2011
Preventive fogging is defined as space spraying of insecticide against mosquitoes in order to prevent outbreak of mosquito borne infection. Despite provision of various preventive andcontrol activities against dengue and chikungunya infection by Ministry
Abdullah, Wan Omar   +5 more
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Impact of a Universal Nirsevimab Prevention Program Against Respiratory Syncytial Virus Bronchiolitis in Infants in Sicily (Italy) During the 2024–2025 Epidemic Season: A Retrospective Cohort Study

open access: yesVaccines
Objectives: The introduction of universal prophylaxis with Nirsevimab represents a major innovation in preventing respiratory syncytial virus (RSV) infections in newborns.
Claudio Costantino   +22 more
doaj   +1 more source

Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects

open access: yesMarine Drugs, 2013
Many marine-derived polysaccharides and their analogues have been reported as showing anticancer and cancer preventive properties. These compounds demonstrate interesting activities and special modes of action, differing from each other in both structure
Sergey N. Fedorov   +3 more
doaj   +1 more source

Planning long-term maintenance for electric vehicle charging infrastructure using the Reliability Centered Maintenance (RCM) method [PDF]

open access: yes, 2012
Electric vehicles (EVs) are mainly known for their advantages as emission free, energy efficient and noiseless transport, but electric mobility has never matured in the automotive market and it remains in the shadow of the internal combustion engine (ICE)
LIOCE, LUIGI
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Private Health Insurance Market Reforms in the Patient Protection and Affordable Care Act (ACA) [PDF]

open access: yes, 2012
[Excerpt] The private health insurance provisions in the Patient Protection and Affordable Care Act (P.L. 111-148, ACA, as amended) include market reforms that impose requirements on private health insurance plans.
Fernandez, Bernadette, Mach, Annie L
core   +5 more sources

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