Results 121 to 130 of about 36,512 (299)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

CYTOKINE MODULATION IN CARDIAC SURGERY: CASE SERIES

Фундаментальная и клиническая медицина, 2018
Аim. Extracorporeal circulation, temporary aortic cross-clamping, cardioplegic arrest, perioperative heart failure, and comorbidities all are among the leading risk factors of a systemic inflammatory response syndrome (SIRS), which in some cases ...
DMITRIY L. Shukevich, ARTEM S. Radivilko, EGOR S. Sardin, ROMAN A. Kornelyuk, MIKHAIL S. Rubtsov, VERA G. Matveeva, EVGENIY V. Grigoriev   +6 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Silver Diamine Fluoride: Caries Arrest And Aesthetic Smile Rehabilitation

International Dental Journal
Introduction: Silver diamine fluoride (SDF), a minimally invasive topical agent, has gained recognition for its capacity to arrest dental caries. Emerging evidence supports SDF’s role in bridging preventive and restorative dentistry, aligning with the ...
Maxstein M. Abuzaid, Chun Hung Chu
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Cardiac arrest of cardiogenic origin [PDF]

Srčani zastoj kardiogenog podrijetla, iznenadni prestanak srčane aktivnosti zbog srčanih uzroka, predstavlja značajan javnozdravstveni izazov. Ovaj diplomski rad govori o ključnim komponentama kardiogenog srčanog zastoja, s naglaskom na mehanizmima ...
Lonza, Bruno
core   +2 more sources

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Characteristics and outcomes of bath-related out-of-hospital cardiac arrest in Japan [PDF]

Kosuke Kiyohara, Chika Nishiyama, Sumito Hayashida, Tasuku Matsuyama, Toshihiro Hatakeyama, Tomonari Shimamoto, Junichi Izawa, Tomoko Fujii, Yusuke Katayama, Taku Iwami, Tetsuhisa Kitamura, Characteristics and Outcomes of Bath-Related Out-of-Hospital ...
Hatakeyama, Toshihiro, Hayashida, Sumito, Matsuyama, Tasuku, Shimamoto, Tomonari, Kitamura, Tetsuhisa, Nishiyama, Chika, Fujii, Tomoko, Kiyohara, Kosuke, Katayama, Yusuke, Iwami, Taku, Izawa, Junichi   +10 more
core   +1 more source