Results 191 to 200 of about 4,835,037 (304)

Extreme Temperatures and Missed Pediatric Preventive Care Visits.

JAMA Netw Open
Mayne SL, Ramachandran J, Sharma P, Ceasar J, Powell M, Jenssen BP, Fiks AG.   +6 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Men's Access to Medical and Preventive Care in Almaty: A Cross-Sectional Study by Occupation. [PDF]

Am J Mens Health
Tolganbayeva K, Abikulova A, Kulzhanov M, Seyduanova L, Abuov J, Kosherbayeva L.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Adoption of the Reference Framework for Preventive Care for Older Adults: a study of primary care physicians. [PDF]

Fam Med Community Health
Zhong CC, Chen M, Yang Z, Li Z, Lo CY, Wong WC, Huang J, Wong MC.   +7 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Associations of Social and Physical Isolation With Material Deprivation and Inadequate Use of Preventive Care in the United States. [PDF]

Ann Fam Med
Riegler J, Han S, Stoianova L, Karjala D, Williams P, Balagopal G, Dwyer I, Chennojwala A, Rastas C, McCormick D, Gaffney A.   +10 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Disparities in cancer screening and preventive care access among LGBTQ+ populations: A cross-sectional study. [PDF]

J Family Med Prim Care
Pustake M, Garikiparthy V, Ganiyani MA, Ogedegbe OJ, Joshi S, Khosla AA, Syed S, Harisingani A, Tiwari N, Saowapa S, Ongsyping S, Gomez J, Corral J, Garje R.   +13 more
europepmc   +1 more source