Results 231 to 240 of about 4,835,037 (304)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Preventive Care and Screening Adherence Among Women Surviving Breast Cancer. [PDF]

Cancers (Basel)
Zisa AJ, Statman MR, Sleiman MM, Liu D, Fleischmann A, Tercyak KP.   +5 more
europepmc   +1 more source

Long-term care prevention

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2012
openaire   +3 more sources

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Cluster-Based Immunization Patterns in Diabetes Mellitus: Insights for Personalized Preventive Care. [PDF]

J Pers Med
Gisinger T, Kautzky-Willer A, Leutner M.
europepmc   +1 more source

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi, Damiano Marastoni, Agnese Tamanti, Pietro Biasi, Valentina Visani, Annalisa Colombi, Tom A. Fuchs, Monica Sicchieri, Chiara Eccher, Francesco Guarnaccia, Milena Calderone, Valentina Camera, Francesca Benedetta Pizzini, Roberta Magliozzi, Marco Castellaro, Massimiliano Calabrese   +15 more
wiley   +1 more source

Socio-economic and insurance factors in preventive care: A two-stage weighted structural analysis. [PDF]

Dialogues Health
Nkouaga F.
europepmc   +1 more source

Relocating pediatric, hospital-based care towards preventive care: a qualitative study on modular care provision for children with developmental disabilities. [PDF]

Eur J Pediatr
Peters VJT, Caspers E, Meijboom BR, Hoofwijk S, Verbeek INE, Gelder CMD, Bok LA.   +6 more
europepmc   +1 more source

Utilizing Telehealth Counseling Sessions to Improve the Process and Delivery of Secondary Preventive Care for Women with Atherosclerotic Cardiovascular Disease. [PDF]

Womens Health Rep (New Rochelle)
Zachariah K, Steitieh D, Newbury D, Sasser L, Narula N, Amin N.   +5 more
europepmc   +1 more source

Barriers to preventive care among US adults of multiple races eligible for type 2 diabetes screening: an observational study. [PDF]

BMC Public Health
Koyama AK, Onufrak S, Bullard KM, Xu F, Papali'i M, Miyamoto Y, Saelee R, Pavkov ME.   +7 more
europepmc   +1 more source