Results 151 to 160 of about 1,618,312 (332)

Environmental and economic sustainability in cultural heritage preventive conservation: LCA and LCC of innovative nanotechnology-based products

open access: yesCleaner Environmental Systems, 2023
M. Menegaldo   +7 more
semanticscholar   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Bio-Inspired 3D-Printed Modular System for Protection of Historic Floors: From Multilevel Knowledge to a Customized Solution

open access: yesHeritage
Historic floors, including mosaics, stone slabs, and decorated pavements, are fragile elements that can be easily damaged during restoration works. Risks arise from falling tools, concentrated loads of scaffolding or equipment, and the repeated passage ...
Ernesto Grande   +3 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Reporting on the Fountains and Monuments in Turin Project: A Proposal for the Preventive and Planned Conservation of Outdoor Cultural Heritage

open access: yesHeritage
The conservation of cultural heritage increasingly requires a transition from emergency restoration to preventive and planned strategies supported by systematic data management. Within this context, this paper, conceived as a project report, presents the
Francesca Bocasso   +4 more
doaj   +1 more source

Learning in an age of digital networks

open access: yes, 2010
The final years of the twentieth century and early years of the twenty first century have been marked by the rapid rise of digital and networked technologies.
Jones, Chris, Sclater, Niall
core  

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Les bons réflexes en conservation préventive

open access: yesLes Nouvelles de l’Archéologie, 2013
Anne-Laure Brives   +3 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Formulation of Mesoporous Silica Nanoparticles for Controlled Release of Antimicrobials for Stone Preventive Conservation. [PDF]

open access: yesFront Chem, 2020
Presentato A   +5 more
europepmc   +1 more source

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