Results 101 to 110 of about 2,021,702 (360)

Geographic Variations in Public Health Spending: Correlates and Consequences [PDF]

open access: yes, 2009
Summarizes research linking economic, political, bureaucratic, and other factors with geographic variations in public health spending and higher public health spending on preventive programs with lower healthcare spending.

core  

Refractory chronic migraine. a consensus statement on clinical definition from the European Headache Federation [PDF]

open access: yes, 2014
The debate on the clinical definition of refractory Chronic Migraine (rCM) is still far to be concluded. The importance to create a clinical framing of these rCM patients resides in the complete disability they show, in the high risk of serious adverse ...
MARTELLETTI, Paolo   +8 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Healthcare Research for Disease Prevention

open access: yesInternational Healthcare Review (online), 2022
The last couple of years have shown the world that there's really no individual health without public health, proving the fundamental importance of cross-sectoral health policies, a constant eye on disease prevention and a baseline preoccupation with tackling inequalities.
openaire   +1 more source

Owner and veterinary surgeon perspectives on the roles of veterinary nurses and receptionists in relation to small animal preventive healthcare consultations in the United Kingdom

open access: yesThe Veterinary Record, 2018
Veterinary receptionists and veterinary nurses rarely feature in published practice-based research, yet are integral to small animal veterinary practice in the UK.
Z. Belshaw   +3 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

REFORMING THE DELIVERY OF PUBLIC DENTAL SERVICES IN IRELAND: POTENTIAL COST IMPLICATIONS. ESRI RESEARCH SERIES NUMBER 80 APRIL 2019 [PDF]

open access: yes, 2019
This report details the results of an analysis of the potential cost implications of proposed changes to aspects of the model of delivery of publicly-financed dental services in Ireland, as set out in the new National Oral Health Policy (Department of ...
Nolan, Anne
core  

CoachAI: A Conversational Agent Assisted Health Coaching Platform

open access: yes, 2019
Poor lifestyle represents a health risk factor and is the leading cause of morbidity and chronic conditions. The impact of poor lifestyle can be significantly altered by individual behavior change.
Fadhil, Ahmed   +2 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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