Results 61 to 70 of about 1,464,211 (246)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Asymmetry in the stock price response to macroeconomic shocks: evidence from the Korean market

Journal of Business Economics and Management, 2018
This study investigates stock price movements in response to macroeconomic shocks, allowing for asymmetry in this relationship. Given Ferson’s (1989) finding that large and small stocks can exhibit different risk behaviors, we examine the behaviors of ...
Geul Lee, Doojin Ryu
doaj   +1 more source

Empirical Evidences from a Coffee Paradox: An Export Supply/Price Asymmetry Approach [PDF]

This paper aims to determine the solidity of the notion of the "coffee paradox" using annual data from 1977 to 2007. In the confines of an export supply model, we analyze the effects of export coffee price on export volume.
Kennedy, P. Lynn, Kang, Hyunsoo
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

BLOCKCHAIN TRANSPARENCY AS A DIGITAL GOVERNANCE MECHANISM: EVIDENCE FROM PRICE TRANSMISSION AND VALUE DISTRIBUTION IN AGRIBUSINESS SUPPLY CHAINS

Jurnal Ilmiah Ilmu Terapan Universitas Jambi
Price transmission asymmetry and unequal value capture remain persistent inefficiencies in smallholder-based agro-processing chains. This study investigates whether blockchain-enabled transparency functions as digital governance that improves price ...
D Iwan Riswandi
doaj   +1 more source

Spatial Asymmetry in Farm-Retail Price Transmission Associated with Fluid Milk Products [PDF]

Testing for asymmetric price transmission and calculating elasticities of price transmission are of great importance in applied economics. We analyze the behavior of tests for asymmetry according to the conventional Houck approach and to the von Cramon ...
Sherwell, Pablo, Capps, Oral, Jr.
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Price transmission in the Hungarian pork market

Agricultural and Food Economics
This study examines price transmission dynamics in the Hungarian pork market from 2017 to 2023, focusing on the effects of price controls implemented to combat inflation.
Tibor Bareith, Imre Fertő, Szilárd Podruzsik   +2 more
doaj   +1 more source

Timing the market: the economic value of price extremes

Financial Innovation, 2018
By decomposing asset returns into potential maximum gain (PMG) and potential maximum loss (PML) with price extremes, this study empirically investigated the relationships between PMG and PML. We found significant asymmetry between PMG and PML.
Haibin Xie, Shouyang Wang
doaj   +1 more source