Results 31 to 40 of about 2,484 (165)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Consumer Inertia and Dynamic Price Competition
Gospodarka Narodowa. The Polish Journal of EconomicsThe aim of this research is to study firms’ decisions about price and quality in a setting where consumers cannot fully evaluate products and must rely on anecdotal evidence to make choices.
Bartłomiej Wiśnicki
doaj +1 more source
BRICS Law Journal, 2020 The authors examine certain legal problems of antitrust regulation in the digital economy facing the international community, including BRICS member countries.
A. Spiridonova, E. Juchnevicius
doaj +1 more source
Sellers’ Pricing Policy in Spatial Competition Models (a case study of the Russian rolled product market) [PDF]
Пространственная экономика, 2011 The article views competition in the rolled section market. The hypotheses about price discrimination, competition according to Cournot or Hotelling being present at this market, have been tested.
Torbenko A. M.
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Market Entry, Product Quality And Price Competition
Studies in Business and Economics, 2015 We study an entrant firm’s product quality choice and the price competition arising between the entrant and the incumbent firm. We show that the entrant firm should introduce a relatively higher (lower) quality than the incumbent firm when the consumers’
Mathur Sameer, Dewani Prem Prakash
doaj +1 more source
Ouverture de ‘Marketing Research and Global Markets’
Symphonya, 2003 Global markets express a new vision of market research and of marketing research, consistent with the information needs of complex organisations (generally network-based) working with several decision-making points (characterised by high-level ...
Silvio M. Brondoni
doaj +1 more source
Price and Quantity Competition under Vertical Pricing
Games, 2023 We consider a vertically related market where one quantity-setting and another price-setting downstream firm negotiate the terms of a two-part tariff contract with an upstream input supplier.
Debasmita Basak
doaj +1 more source