Results 151 to 160 of about 947,110 (306)

Competition in Retail Electricity Supply [PDF]

This paper presents an analysis and defence of competition in retail electricity supply. It includes some account of its development in the UK over the last dozen years, to the point where all retail price controls have now been removed.
Stephen C. Littlechild
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

"Racial Preferences in a Small Urban Housing Market: A Spatial Econometric Analysis of Microneighborhoods in Kingston, New York" [PDF]

This paper use spatial econometric models to test for racial preferences in a small urban housing market. Identifying racial preferences is difficult when unobserved neighborhood amenities vary systematically with racial composition.
Anh Pham, Michael Smith, Sanjaya DeSilva
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Evolution of Grain Policy Beyond Europe: Ottoman Grain Administration in the Late Eighteenth Century [PDF]

During the second half of the eighteenth century, the Ottoman policy-makers adopted a more liberal attitude towards price formation in the Ottoman grain markets.
Seven Agir
core  

Defining the Systemic Response to Flight After Polytrauma in a Murine Model. [PDF]

Mil Med
Becker ER, Wetmore GC, Wattley LJ, Price AD, England L, Schuster RM, Pritts TA, Goodman MD.   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Neuropathological measures of increased tau phosphorylation across the Down syndrome lifespan. [PDF]

Acta Neuropathol
Pascual JR, Rivera I, Nguyen H, Ngo PT, Hoang A, Andrews EJ, Rouanet J, Wright ST, Sordo L, Kofler J, Ikonomovic MD, Lai F, Mapstone M, Christian BT, Handen BL, Lott IT, Doran E, Hom CL, Harp J, Schmitt F, Tudorascu DL, Ances BM, Phelan M, Liu L, Flores-Aguilar L, Head E, Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC-DS) Investigators.   +26 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Macroeconomic Effects of Price Controls: The Role of Market Structure [PDF]

Price controls were part of Israel's stabilization program of July 1985. Some results of the program seem to be inconsistent with competitive macroeconomic models.
Elhanan Helpman
core