Results 191 to 200 of about 770,462 (312)

On quality standards and the timing of pharmaceutical investment. [PDF]

Front Public Health
Wei W.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Diagnosis of the first few cases of a novel respiratory pathogen: the FFX-Dx protocol. [PDF]

Bull World Health Organ
Denkinger CM, Cunningham J, Faehling V, Brümmer LE, Hanson K, Molenkamp R, Miller MB, Marcato AJ, Price DJ, Ciesek S, Agogo E, Fitchett J, Ströher U, Yadav PD, Bergeri I, Boddington NL, Pollock NR.   +16 more
europepmc   +1 more source

Market hog price discovery

Kansas Agricultural Experiment Station Research Reports, 1999
Ted C Schroeder, J Mintert
openaire   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Research and Industry for Human Health Enabled by Detergent Chemistry. [PDF]

Chempluschem
Urner LH.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

KGAP: An RDF knowledge graph of agricultural commodity prices. [PDF]

Data Brief
Soares FM, Ferreira Pires L, Corrêa FE, Bonino da Silva Santos LO, Braghetto KR, Moreira DA, Drucker DP, Delbem ACB, Saraiva AM.   +8 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A primer on prescription drug pricing benchmarks in the United States. [PDF]

J Manag Care Spec Pharm
Hung A, Dickson S.
europepmc   +1 more source