Results 221 to 230 of about 2,488,526 (252)

Towards an equitable future of global photovoltaic waste recycling. [PDF]

Nature
Wang C, Zuo J, Chen X, Chang R, Yuan P, Feng K, Xin Y, Liu X, Tian P, Li J, Esguerra JL, Li J.   +11 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

A Multiregional Decentralized Clinical Trial Program to Improve Access.

JAMA Netw Open
Haddad TC, Mercado LA, Le-Rademacher JG, Enarson DA, Sener U, Kumar A, Price KA, Juhn YJ, Cartin-Ceba R, Colon-Otero G, Willman CL, Garovic VD, Kottschade RS.   +12 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Molecular biology and integrated strategies for activating cryptic biosynthetic gene clusters toward next-generation antibiotic discovery. [PDF]

Front Bioinform
Pattapulavar V, Ramanujam S, Yellampalli A, Badiginchala HS, Christopher JG.   +4 more
europepmc   +1 more source

Transcriptomic analysis and high throughput functional characterization of human induced pluripotent stem cell derived sensory neurons. [PDF]

Neurobiol Pain
Truong V, Brougher J, Strassmaier T, Lu YL, George D, Price TJ, Obergrussberger A, Haedo RJ, Fertig N, Walsh P.   +9 more
europepmc   +1 more source

Do carbon policy shocks move stocks? evidence from China's carbon market. [PDF]

Carbon Balance Manag
Peng J, Zeng Y, Fu S, Tian J.
europepmc   +1 more source

Waste-to-energy technology selection and capacity planning in a multi-facility waste management system. [PDF]

Discov Energy
Saif A, Zoroufchi Benis K.
europepmc   +1 more source

Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversity. [PDF]

Theor Appl Genet
Zhao D, Lin M, Taniguti CH, Sandercock AM, Chen S, Babiker E, Bassil NV, Brummer EC, Camacho JR, Chatwin W, Chen SY, Clare SJ, da Silva Pereira G, David M, Fraher SP, Hardigan M, Hilton A, Hislop LM, Irish BM, Kante M, Kim TH, Lee CW, Lindqvist-Kreuze H, Loarca J, Lu PH, Medina Culma CA, Jiménez Morales JF, Polashock J, Price JH, Riday H, Samac DA, Sandhu D, Ssali R, Castro Vásquez RM, Wadl PA, Wang X, Webster SA, Xu Z, Yencho GC, Beil CT, Sheehan MJ.   +40 more
europepmc   +1 more source

Clinical benefit, price and epidemiology of orphan drugs approved in China: a cross-sectional analysis of orphan drug policy (ODP) in China. [PDF]

BMJ Open
Yuan J, Li M, Jiang B, Lu ZK, Zhao J, Jiang X.   +5 more
europepmc   +1 more source