Results 201 to 210 of about 330,118 (264)

Evaluating the Use of Zip Codes as a Proxy for Socioeconomic Status in Surgeon Ranking Systems: A Single-Center Arthroplasty Study. [PDF]

Cureus
Morris K, Price A, Ibrahim AF, Opella K, Steward M, Henderson B, Gaschen PD, Hernandez EJ, Ghanem D, Brindley G.   +9 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Blockchain-enabled strategic optimization: A decision analytics framework for multinational enterprises' e-commerce entry model. [PDF]

PLoS One
Deng L, Hu X, Xiao Y.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Plant-based protein foods are less sensitive to price changes than animal-based ones, with differences across income and education levels. [PDF]

Commun Sustain
McRae C, Saarijärvi H, Nevalainen J, Fogelholm M, Ma Y, Dubé L.   +5 more
europepmc   +1 more source

A comprehensive dataset for uncovering housing price drivers in emerging cities: Nanning as a case study. [PDF]

Data Brief
Lin W, Wu K, Zhang X, Gu X, Jiang M, Wang J, Han F.   +6 more
europepmc   +1 more source

Sustainable closed-loop supply chain management for a two-warehouse system with trade-credit and emissions constraints under dynamic demand. [PDF]

Sci Rep
Vishnoi M, Deepi D, Singh SR, Sarkar B.
europepmc   +1 more source

An advanced reliability reserve incentivizes flexibility investments while safeguarding the electricity market. [PDF]

iScience
Klaucke F, Neuhoff K, Roth A, Schill WP, Stolle L.   +4 more
europepmc   +1 more source

The Price Level

, 1914
openaire   +1 more source